Article

Fatal late coronary thrombosis after implantation of a radioactive stent: postmortem angiographic and histologic findings--case report.

Department of Cardiology, Clinic for Internal Medicine II, University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
Radiology (impact factor: 5.73). 08/2001; 220(1):142-4. pp.142-4
Source: PubMed

ABSTRACT Postmortem angiography and histologic analysis of a fatal coronary thrombosis 4 months after implantation of a radioactive stent are described. Histologic findings suggested incomplete re-endothelialization in the segment with the stent. Ionizing radiation may delay re-endothelialization after revascularization, thus maintaining the thrombogenicity of the irradiated vessel segment. Thus, prolonged antiplatelet therapy should be considered after intravascular radiation therapy.

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Keywords

antiplatelet therapy
 
histologic analysis
 
Histologic findings
 
incomplete re-endothelialization
 
intravascular radiation therapy
 
Ionizing radiation
 
radioactive stent
 
thrombogenicity
 

P Wexberg