Article

Predictors, prodromes and incidence of postpartum depression.

Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Journal of Psychosomatic Obstetrics & Gynecology (impact factor: 1.39). 07/2001; 22(2):103-12. pp.103-12
Source: PubMed

ABSTRACT The purpose of this study was to determine the incidence of clinically significant depression occurring between 1 and 4 months postpartum and to investigate whether somatic complaints, subsyndromal depressive symptoms, or birth-related concerns among non-depressed women at 1 month were predictive of postpartum depression. This is a prospective cohort study of 465 women from the Wisconsin Maternity Leave and Health Project (WMLHP). Women who were not depressed at 1 month postpartum were reassessed 3 months later for depression occurring at any time in the interval between 1 and 4 months postpartum. Depression was defined as either meeting the criteria for major depression on the National Institute of Mental Health (NIMH) Diagnostic interview Schedule (DIS) or scoring above 15 on the Center for Epidemiologic Studies Depression Scale (CES-D). Physical symptoms were assessed by an adapted Health Responses Scale. Other measures were developed specifically for the WMLHP. Of 465 women, 27 (5.8%) became clinically depressed between 1 and 4 months postpartum. In a logistic regression analysis, four variables (maternal age, depression during pregnancy, thoughts of death and dying at 1 month postpartum, and difficulty falling asleep at 1 month postpartum) were predictive of depression at 4 months postpartum. Breast-feeding, mode of delivery, family income, parity and mother's education did not predict depression. The existence of subsyndromal depressive symptoms, particularly thoughts of death and dying, may represent a prodromal phase of depression and should alert clinicians to the possibility of future postpartum depression. Women with a history of depression during pregnancy should be monitored for signs of postpartum depression for a minimum of 4 months. Obstetricians are in a unique position during the postpartum check-up to screen women for these predictors of future postpartum depression and possibly to avert the development of a clinically significant depressive episode.

0 0
 · 
0 Bookmarks
 · 
25 Views
  • Source
    Article: Perinatal common mental disorders and breastfeeding duration: A cohort study from Brazil
    [show abstract] [hide abstract]
    ABSTRACT: Objective: The aim of this study was to prospectively evaluate the relationship between common mental disorders (CMD) during the antenatal and postpartum periods and breastfeeding for less than four months (BF < 4). Methods: A prospective cohort study conducted between May 2005 and March 2007 included 701 pregnant women recruited from primary care clinics of the public sector in São Paulo, Brazil. The following instruments were in effect: antenatal and postnatal CMD were measured with the Self Report Questionnaire (SRQ-20); social support was assessed with a Brazilian version of the scale used in the Medical Outcomes Study; and questionnaires were employed to obtain socio-demographic, socioeconomic, obstetric, and breastfeeding information. The primary outcome was breastfeeding for BF < 4. Crude and adjusted risk ratios (RR), with 95% confidence intervals (95% CI), were calculated using Poisson regression to examine the associations between BF < 4 and CMD. Results: BF < 4 occurred in 22.8% of the cohort. In the univariate analysis BF < 4 was associated with lower maternal age, not having a partner, lower wealth score, having a previous miscarriage, newborn oral tracheal intubation, and CMD in the antenatal and postpartum periods. In the multivariate analysis, the following variables were independently associated with BF < 4: maternal age (RR: 0.62 (95% CI: 0.39–0.98), newborn oral tracheal intubation (RR: 1.85 (95% CI:1.28–2.65) and CMD during both the antenatal and postpartum (RR: 1.38 (95% CI: 0.98 : 1.95) periods. Conclusion: Among women who have a CMD both during the antenatal and postpartum periods, there is a decreased likelihood for breastfeeding longer than 4 months.
    Journal of Neonatal-Perinatal Medicine 01/2012; 5:135-142.
  • Article: perinatal depression in a cohort study of Iranian women
    [show abstract] [hide abstract]
    ABSTRACT: Introduction: Childbearing years in the women’s life are associated with the highest risk of depression. Despite the results of some studies that suggested, depression during pregnancy has been associated with poor prenatal care, substance abuse, low birth weight, and preterm delivery and introduced antenatal depression and anxiety as predictors of postnatal depression, researches during past 25 years have focused mostly on postpartum depression so depression during pregnancy is relatively neglected. Materials and methods: We studied depression during third trimester of pregnancy and after delivery, using prospectively gathered data from a cohort of 1898 women. We compared depressive symptom score and the proportion of mothers above a threshold, to indicate probable depressive disorder at each stage. Results: Point prevalence of depressed pregnant women (clinical depression) based on BDI score greater than 20 in last trimester of pregnancy, was 22.8% and postnatal rate of depression based on EPD score greater than 12 between 6 to 8 weeks after delivery, was 26.3%. Incidence of PPD in 6 to 8 weeks after delivery in those who were not clinically depressed during pregnancy was, 20.1%. Discussion: We found that history of depression, unplanned pregnancy; being housewife and having 3 or more children were variables with significant relation to ante partum depression. Two main risk factors for post partum depression in this cohort study, were previous history of depression and depression during current pregnancy that highlight the importance of these two variables assessment during pregnancy in order to facilitate timely identification of women at risk.
    Journal of Research in Medical Sciences. 01/2010;
  • Article: Perinatal depression in a cohort study on Iranian women.
    [show abstract] [hide abstract]
    ABSTRACT: Childbearing years in the women's life are associated with the highest risk of depression. In this study depression in third trimester of pregnancy and after delivery was studied. Depressive symptom score and the proportion of mothers above a threshold were compared to indicate probable depressive disorder at each stage. This prospective cohort study was conducted in rural areas of Isfahan province of Iran from September 2007 to January 2008. Subjects were all in their third trimester and followed up from the beginning of the study to 6-8 weeks postpartum. At all, 2156 pregnant women completed the self report questionnaires but 258 were excluded because they were incomplete and final analysis was done with 1898 samples. At the final stage the sample size was decreased to 1291. The prevalence of depression based on BDI score greater than 20 in last trimester of pregnancy, was 22.8% and rate of depression based on EPD score greater than 12 between 6 to 8 weeks after delivery, was 26.3%. Incidence of Post Partum Depression (PPD) in 6 to 8 weeks after delivery in those who were not clinically depressed during pregnancy was 20.1%. Results showed that history of depression, unplanned pregnancy, being housewife and having 3 or more children had significant relation with ante partum depression. Two main risk factors for post partum depression are previous history of depression and depression during current pregnancy. It is important to assess these variables during pregnancy in order to facilitate timely identification of women at risk.
    Journal of research in medical sciences 01/2010; 15(1):41-9. · 0.46 Impact Factor

Keywords

4 months
 
adapted Health Responses Scale
 
clinically depressed
 
clinically significant depression
 
clinically significant depressive episode
 
Epidemiologic Studies Depression Scale
 
family income
 
future postpartum depression
 
Health Project
 
logistic regression analysis
 
major depression
 
maternal age
 
Mental Health
 
mother's education
 
National Institute
 
non-depressed women
 
postpartum depression
 
prospective cohort study
 
screen women
 
subsyndromal depressive symptoms