Article

Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

Department of Chemistry, University of Aberdeen, Aberdeen, Scotland, United Kingdom
Phytochemistry (Impact Factor: 3.35). 09/2001; 57(8):1273-6. DOI: 10.1016/S0031-9422(01)00084-X
Source: PubMed

ABSTRACT Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay.

1 Follower
 · 
129 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: Essential oil composition of Centaurea stenolepis Kerner flowers and stems were investigated with GC, GC/MS. Flowers and stems of C. stenolepis had very low essential oil yield <0.01% (v/w). Twenty eight compounds were identified in the flower oils which represent 53.5% of the oil. Main components of the flower oils include caryophyllene oxide 12.6%, hexadecanoic acid 10.6% and β-Eudesmol 7.2%. Forty compounds were identified in the stem oils which represent 74.2% of the oil. Main components of the stem oils include hexadecanoic acid 38.4% and phytol 12.9%. Both flower and stem oils were rich on oxygenated sesquiterpene hydrocarbons and fatty acids. The present study shows that flower oil of C. stenolepis from Turkey is rich in sesquiterpene hydrocarbons, hexadecanoic acid and stem oil is rich in higher alkanes, fatty acids unlike the previous reports. These differences observed in both studies could be related to differences in collection time, ecological factors, climatic conditions, soil conditions, methods employed in the analysis and genetical differences. However differences in the biosynthetic origins of the main compounds in both studies strongly suggest chemotype variation in this species exist. In order to determine the exact situation in this species essential oil, non-volatile secondary metabolite comparisons on samples of C. stenolepis from different locations should be done together with DNA comparisons and seasonal variation studies.
    45th International Sympossium on Essential Oils, İstanbul/Turkey; 09/2014
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Essential oil composition of Centaurea stenolepis Kerner flowers and stems were investigated with GC, GC-MS. Flowers and stems of C. stenolepis had very low essential oil yield <0.01 % (v/w). Twenty eight compounds were identified in the flower oil which represent 53.5 % of the oil. Main components of the flower oil include caryophyllene oxide 12.6 %, hexadecanoic acid 10.6 % and β-Eudesmol 7.2 %. Forty compounds were identified in the stem oils which represent 74.2 % of the oil. Main components of the stem oils include hexadecanoic acid 38.4 % and phytol 12.9 %. Both flower and stem oils were rich on oxygenated sesquiterpene hydrocarbons and fatty acids.
    Journal of essential oil-bearing plants JEOP 02/2015; 17(6):1268. · 0.19 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Ambrosia peruviana has been reported as an anti-infective and anti-parasitic plant in the ethno-pharmacological environment. Given the high rates of bacterial and parasitic resistance against commercial drugs recorded, we performed the preliminary phytochemical screening following Sanabria's method and biological tests against clinical bacterial isolates, dog parasites, and Artemia salina.
    09/2010; 14(3):186-194. DOI:10.1016/S0123-9392(10)70110-7