Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)

Department of Chemistry, University of Aberdeen, Aberdeen, Scotland, United Kingdom
Phytochemistry (Impact Factor: 3.35). 09/2001; 57(8):1273-6. DOI: 10.1016/S0031-9422(01)00084-X
Source: PubMed

ABSTRACT Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay.

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