Cystic neoplasms of the pancreas - Benign to malignant epithelial neoplasms
ABSTRACT Clinical presentation and state-of-the-art imaging permit the differentiation of most cystic pancreatic neoplasms not only from other cystic pancreatic disorders but also from one another. The differentiation of serous cystic lesions from the mucinous neoplasms (cystadenoma or carcinoma and IPMT) is crucial because of the radically different biological characteristics of these two neoplasms. Although mucinous cystic neoplasms should be resected because of their premalignant or overtly malignant tendency, most patients with serous neoplasms require no operative intervention unless they are symptomatic. IPMT is best treated by a total pancreatectomy, although lesser subtotal resections should be strongly considered depending on patient age, medical comorbidity, and psychosocial situations.
- SourceAvailable from: Shailesh Shrikhande
- "The incidence of radiologically detected pancreatic cystic neoplasms in screening varied from 0.2%  when ultrasonography was used to 0.7%  in a study using CT and MRI scans. Serous cystic neoplasms predominantly affect women (65%), with an average age of 62 years (range 35 Á84 years) . They account for 32 Á39% of cystic tumours of the pancreas . "
Article: Cystic tumours of the pancreas[Show abstract] [Hide abstract]
ABSTRACT: Pancreatic carcinoma accounts for the most dismal survival among all malignancies with 5-year survival rates approaching 5%. The reason for this, besides the inherent biologic nature of the disease, is the fact that the patients tend to present late in the disease. We present a review of the current published data on cystic neoplasms of the pancreas, which though rare, constitute an important subgroup of pancreatic neoplasms that have a better prognosis and are potentially curable lesions.HPB 02/2007; 9(4):259-66. DOI:10.1080/13651820701435287 · 2.05 Impact Factor
- "However, Sarr and his colleagues  have classified these rare neoplasms into a more simplified and practical working classification, which is as follows: • serous cystic neoplasms • mucinous cystic neoplasms • intraductal papillary mucin-producing neoplasms • other less common neoplasms. "
Article: Cystic pancreatic neoplasms[Show abstract] [Hide abstract]
ABSTRACT: Cystic pancreatic neoplasms are uncommon, but are being seen more frequently due to the widespread use of cross-sectional imaging. In this article, we will address the clinical and imaging features of the more commonly seen neoplasms. Points of differentiation between these neoplasms, the use of cyst fluid analysis and an approach to the incidentally discovered cystic mass will be addressed.Cancer imaging : the official publication of the International Cancer Imaging Society 01/2003; 3(2):111-116. DOI:10.1102/1470-7330.2003.0007 · 1.29 Impact Factor
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ABSTRACT: Cystic neoplasms comprise 1-10% of all pancreatic neoplasms. Most authors recommend resection due to the difficulties in differentiating benign from malignant tumors prior to operation. We performed an analysis on the radical surgical handling of patients with cystic neoplasms of the pancreas. We analyzed data of all patients with pancreatic neoplasms who were treated by potentially curative surgical treatment by a single surgeon (A.D.C.). Postoperative survival and complications were recorded. Between August 1983 and November 2003, the aforementioned surgeon performed 77 pancreatic resections for pancreatic tumors. Nine of those operations were performed for cystic neoplasms of the pancreas. All patients submitted to partial pancreatic resections were discharged in good health. The patient that underwent a total pancreatectomy died nine days after the procedure. At a mean follow up of 44 months, there has been one local recurrence with death. Cystic tumors of the pancreas accounted for 11.7 % of the neoplasms studied in our series. Resection of those neoplasms attained by distal pancreatectomy is a safe procedure. PD is a risky procedure and should be viewed cautiously. Total pancreatectomy remains as a high-risk procedure and should be avoided.Revista de gastroenterologia del Peru: organo oficial de la Sociedad de Gastroenterologia del Peru 01/2005; 25(1):42-7.