Article

Cystic neoplasms of the pancreas - Benign to malignant epithelial neoplasms

Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Surgical Clinics of North America (Impact Factor: 1.93). 07/2001; 81(3):497-509. DOI: 10.1016/S0039-6109(05)70139-0
Source: PubMed

ABSTRACT Clinical presentation and state-of-the-art imaging permit the differentiation of most cystic pancreatic neoplasms not only from other cystic pancreatic disorders but also from one another. The differentiation of serous cystic lesions from the mucinous neoplasms (cystadenoma or carcinoma and IPMT) is crucial because of the radically different biological characteristics of these two neoplasms. Although mucinous cystic neoplasms should be resected because of their premalignant or overtly malignant tendency, most patients with serous neoplasms require no operative intervention unless they are symptomatic. IPMT is best treated by a total pancreatectomy, although lesser subtotal resections should be strongly considered depending on patient age, medical comorbidity, and psychosocial situations.

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    • "The incidence of radiologically detected pancreatic cystic neoplasms in screening varied from 0.2% [5] when ultrasonography was used to 0.7% [6] in a study using CT and MRI scans. Serous cystic neoplasms predominantly affect women (65%), with an average age of 62 years (range 35 Á84 years) [7]. They account for 32 Á39% of cystic tumours of the pancreas [8]. "
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    • "However, Sarr and his colleagues [1] have classified these rare neoplasms into a more simplified and practical working classification, which is as follows: • serous cystic neoplasms • mucinous cystic neoplasms • intraductal papillary mucin-producing neoplasms • other less common neoplasms. "
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