Remitting seronegative symmetrical synovitis with pitting edema associated with subcutaneous Streptobacillus moniliformis abscess

Department of Family Medicine, Hospital Txagorritxu, Osakidetza, Vitoria-gasteiz, Spain.
The Journal of Rheumatology (Impact Factor: 3.19). 08/2001; 28(7):1696-8.
Source: PubMed


We describe an 84-year-old woman who developed remitting seronegative symmetrical synovitis with pitting edema (RS3PE) associated with a subcutaneous abscess of the hand due to Streptobacillus moniliformis. Polyarthritis and edema were relieved after therapy with corticosteroids. We review the association of RS3PE to different rheumatologic, neoplastic, or infectious diseases.

5 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: Described here is the case of an 87-year-old man who developed fever, chills and discomfort caused by Streptobacillus moniliformis. This pathogen is one of the causes of rat-bite fever, an uncommon bacterial illness transmitted through a bite or scratch from a rodent or the ingestion of food or water contaminated with rat faeces. Cases of rat-bite fever are rarely reported in Spain. The patient reported no history of rat bite or rodent contact, and the only known risk factor was contact with a dog and a cat that were kept as pets. Streptobacillus moniliformis was isolated in two sets of blood cultures. This case represents what is believed to be the first report of bacteremia due to Streptobacillus moniliformis in Spain.
    European Journal of Clinical Microbiology 05/2003; 22(4):258-60. DOI:10.1007/s10096-003-0891-9 · 2.67 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Streptobacillus moniliformis was identified as etiologic agent of arthritis utilizing a 16S rDNA molecular kit in our clinical laboratory. With the increasing of human contacts with rat as pet, this method would appear suitable to identify fastidious Gram-negative rod involved in arthritis specially when the clinical context is not evocative.
    Diagnostic Microbiology and Infectious Disease 01/2004; 47(4):623-4. DOI:10.1016/S0732-8893(03)00167-6 · 2.46 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: This study analyses the clinical, radiological, evolutive, and immunogenetical characteristics of a series of patients diagnosed with remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome. Reviewed were the clinical charts and human leukocyte antigen (HLA) profiles of all patients treated at a single teaching hospital fulfilling the features of this syndrome according to the definition of McCarty. Twelve cases were detected in ten men and two women aged from 62 to 85 years. Rheumatoid factor was negative in all cases, and antinuclear antibodies (ANA) were positive in two. All patients achieved complete resolution of their condition within 1 year with glucocorticoid (GC) use. Two relapsed after remission but responded again to low doses of GC. Four patients showed clinical and electrodiagnostic studies consistent with carpal tunnel syndrome. No specific HLA association could be found in this report. To date, none of these patients has developed definite rheumatic diseases, infections, or malignant diseases. Although the real nature of the syndrome is still a matter of debate, at least in our context, RS3PE remains a definite condition with an excellent prognosis.
    Rheumatology International 04/2004; 24(2):103-5. DOI:10.1007/s00296-003-0330-3 · 1.52 Impact Factor
Show more