Resistance is futile: Assimilation of cellular machinery by HIV-1

Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA 94305, USA.
Immunity (Impact Factor: 19.75). 12/2001; 15(5):687-90. DOI: 10.1016/S1074-7613(01)00238-2
Source: PubMed

ABSTRACT HIV-1 budding appears to require Vps4 and Tsg101-two proteins that have links to endosomal sorting machinery. A picture emerges wherein divergent viruses recruit endosomal proteins like Tsg101 to gain access to ubiquitin processes that play a crucial role during viral budding.

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