A left-lateralized network for reading Chinese words: A 3T fMRI study

Institute of Neuroscience, National Yang Ming University, T’ai-pei, Taipei, Taiwan
Neuroreport (Impact Factor: 1.64). 01/2002; 12(18):3997-4001. DOI: 10.1097/00001756-200112210-00029
Source: PubMed

ABSTRACT fMRI was used to investigate brain organization for reading in Chinese. Subjects were shown two-character Chinese words. A control task was used to eliminate the non-linguistic visual and motor confounds. Results show that naming of Chinese logographs is characterized by left-lateralized neuronal networks for the processing of orthographic, phonological, and semantic attributes. The orchestration of the middle frontal cortex, superior temporal cortex, superior parietal cortex, basal temporal area and extrastriate cortices of the left hemisphere may manifest the particularity of the central representation of simple word naming in Chinese.

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Available from: Jen-Chuen Hsieh, Aug 12, 2015
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    • "The activation of the left middle frontal gyrus (BAs 9/46) has been reported in several functional neuroimaging studies on Chinese character processing (e.g., Booth et al., 2006; Dong et al., 2005; Kuo et al., 2001, 2004; C.-L. Liu et al., 2006; Tan et al., 2000, 2001a, 2001b). Some suggest that the left middle frontal gyrus is recruited for the intensive visuospatial analysis of Chinese logographs demanded by the visual forms of characters (Tan et al., 2001a, 2001b) and the coordination of phonological or semantic processing required by experimental tasks (Tan et al., 2000, 2001b). "
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    • "We also found the hemispheric asymmetries of the brain structures in both of the two population groups. This confirmed previous brain-asymmetry studies (Kuo et al., 2001, 2003; Tan et al., 2001a,b, 2003, 2000). These results demonstrate the need for lateral and population-specific data processing and analysis (including atlas-based spatial normalization) in modern computational neuroimaging studies of brain structure and function. "
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    • "Neuroimaging studies in adults have also suggested that visuo-orthographic processing is crucial in Chinese reading compared to English reading, and that the visual analyses in Chinese engage bilateral temporo-occipital regions while those in English mainly engage the left hemisphere (Petersen et al. 1989; Bookheimer et al. 1995; Chee et al. 1999; Cohen et al. 2000; Liu and Perfetti 2003; Bolger et al 2005; Tan et al. 2005a; Cao et al. 2009; Kuo et al. 2001; Xue et al. 2005). Greater involvement of right temporo-occipital regions in Chinese might be due to the special features of Chinese characters. "
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