Newer components of enteral formulas

Department of Pediatrics, Northwestern University, Division of Gastroenterology, Hepatology, and Nutrition, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois, USA.
Pediatric Clinics of North America (Impact Factor: 2.12). 03/2002; 49(1):113-25. DOI: 10.1016/S0031-3955(03)00111-1
Source: PubMed


The past decade has seen a paradigm shift in the goals of nutritional care from basic delivery of macronutrient calories to the provision of specific nutrients, which, in addition to supporting growth, have health and disease modulating effects. The appreciation of the central role of nutrition in heath and disease may lead to increased use of a new array of diets that are more specific for underlying health and disease pathophysiologic processes. An improved understanding of disease-specific pathophysiology, and limited but promising data from ongoing clinical trials, are fueling this positive change. Therefore, a greater understanding of rationale for the newer products may lead to improved nutritional and clinical care during health and disease.

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    ABSTRACT: We report our experience of paediatric home enteral nutrition, as there is little detailed evidence published. All patients younger than 18 years commencing treatment between January 1990 and December 2000 were included in this retrospective study. The study covered 416 children and adolescents, corresponding to a total of 243,844 days of home enteral nutrition (HEN). The mean (+/-SD) age of patients commencing treatment was 5.4+/-5.3 years (range 0.1-17.8). Indications were digestive disorders in 35% of patients, neurological and muscular disorders in 35%, malignancy in 11%, failure to thrive in 8%, and miscellaneous ailments in 9%. Enteral feeding comprised commercially available paediatric industrial diets in 36%, adult-type diet in 35% and infant formulas in 29%. Children received enteral feeding by nasogastric tube (53%), or gastrostomy (41%). A mechanical pump was used in 98% of the patients. The mean duration of treatment was 595+/-719 days. HEN can be used while treating a large group of chronic diseases of children. It can be started very early in life and is often prolonged over several years.
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