Inducing lactation: a personal account after gestational 'surrogate motherhood' between sisters.
ABSTRACT In Australia in 1988, Linda Kirkman gestated a baby for her sister, Maggie Kirkman (conceived using Maggie's ovum and IVF). During the pregnancy, a variety of means were used to stimulate lactation. After the birth, several women donated breastmilk as supplements to Maggie's supply. The paper discusses not only the induction of lactation, but the cooperation of women, that enabled a baby to be fed breastmilk exclusively for her first four months.
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ABSTRACT: Plasmin is a protease in milk, which concentration is increased during mastitis. The aim of the study was design and characterize short, tailor made fluorogenic substrates for plasmin to see differences in plasmin activity in healthy milk compared to mastitic milk. According to the specificity matrix of plasmin, containing 125 currently known plasmin substrates, six novel plasmin specific substrates were designed and characterized. Eight other substrates were insensitive for plasmin, which was in line with our expectations. The plasmin-sensitive substrates showed no cross-reactivity with proteases from mastitogenic bacteria in vitro. A proof of concept to distinguish healthy milk from mastitic milk is described. Potentially, these substrates present a rapid alternative to the currently established methodologies to detect mastitis in milk.Veterinary Research Communications 07/2014; 38(4). DOI:10.1007/s11259-014-9611-4 · 1.36 Impact Factor
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ABSTRACT: Although a small minority in the United States, a number of adoptive mothers continue to seek information regarding the induction of lactation. Because of the level of support needed by these women to successfully induce lactation, it is necessary for nurses and other healthcare workers to gain a thorough understanding of the various processes and medications frequently used. Often, women who induce lactation cannot produce enough milk to exclusively breastfeed their infant but find satisfaction in this rigorous process because of the maternal-infant bonding it promotes. The adoptive mother seeking to induce lactation is a unique client in need of highly tailored and personalized care.MCN The American Journal of Maternal/Child Nursing 03/2008; 33(2):76-81; quiz 82-3. DOI:10.1097/01.NMC.0000313413.92291.0f · 0.84 Impact Factor
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ABSTRACT: 'Wonder Bub' and 'Alice in Wonderland' were the bold newspaper headlines when the author's daughter was born in 1988, because she was conceived using her mother's egg and donor sperm, and gestated by her aunt. The technique was described as gestational surrogacy, and Alice was the first in Australia (the second known in the world) to be thus conceived. This event caused interest and controversy not only in Australia, where it took place, but around the world. In the midst of the controversy, the author and her husband had to learn to parent a baby to whom she had not given birth and of whom he was not the genetic father.This paper describes how the extended family worked together to make Alice's birth possible and how her parents developed a narrative through which to make it comprehensible to Alice. The author considers both personal experience and cultural meaning as she reflects on the 13 years since Alice's birth. The paper concludes with comment from Alice at 13.Journal of Reproductive and Infant Psychology 08/2002; 20(3):135-147. DOI:10.1080/026468302760270791 · 0.67 Impact Factor