Article

Turning on the Arp2/3 complex at atomic resolution.

Department of Chemistry, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.
Structure (impact factor: 6.35). 03/2002; 10(2):131-5. pp.131-5
Source: PubMed

ABSTRACT The recently published 2 A X-ray crystal structure of bovine Arp2/3 complex gives us atomic scale insight into Arp2/3-mediated actin nucleation, while cryo-EM work and functional studies begin to fill in exciting mechanistic details.

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Keywords

Arp2/3-mediated actin nucleation
 
bovine Arp2/3 complex
 
functional studies
 
X-ray crystal structure
 

Elizabeth L Borths