Article

Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis.

Department of Analytical Chemistry, University of Barcelona, Spain.
Journal of Chromatography B (impact factor: 2.89). 03/2002; 767(2):313-9. DOI:10.1016/S1570-0232(01)00587-6 pp.313-9
Source: PubMed

ABSTRACT This paper describes a method for residue analysis of difloxacin and sarafloxacin in chicken muscle. Clean-up and preconcentration of the samples are effected by solid-phase extraction (C18) and the determination is carried out by capillary electrophoresis using a photodiode array detection system. The method was validated with satisfying results. The calibration graphs are linear for difloxacin and sarafloxacin from 50 to 300 microg/kg. The limit of detection obtained for difloxacin and sarafloxacin are 10 and 25 microg/kg, respectively, which allows the detection of positive muscle samples at the required maximum residue limits of European Union.

0 0
 · 
0 Bookmarks
 · 
21 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

calibration graphs
 
Clean-up
 
detection
 
European Union
 
photodiode array detection system
 
positive muscle samples
 
required maximum residue limits
 
residue analysis
 
samples
 
satisfying results
 

D Barrón