Article

[First surgery followed by vaginal curietherapy in small-volume uterine cervix cancer: an alternative to the association of uterovaginal curietherapy and surgery].

Service de radiothérapie, institut Bergonié, centre régional de lutte contre le cancer, 229, cours de l'Argonne, 33076 Bordeaux, France.
Cancer/Radiothérapie (impact factor: 1.49). 03/2002; 6(1):10-4. pp.10-4
Source: PubMed

ABSTRACT Evaluate the results of the treatment of small uterine cervix cancer with the association of surgery and postoperative vaginal brachytherapy, without unfavourable prognostic factors.
After radical hysterectomy with lymphadenectomy, 29 women (mean age: 44 years) with carcinoma < 25 mm (26 stage IB1, 3 IIA, mean size: 15 mm) were treated by post-operative prophylactic vaginal brachytherapy using low dose rate. Ovarian transposition was performed at the surgical time in 14 young women (mean age 35 years).
The actuarial specific survival rates at 5 and 10 years were 100% and 90% respectively, with a mean follow-up 75 months. Only one local recurrence was observed. The rate of grade 1 post-operative complication was 7%. The conservation rate of the ovarian function was 85% for young women.
Treatment of small volume uterine cervix cancer using first surgery and post-operative vaginal brachytherapy is a reliable therapeutic option. The results in terms of specific survival and complications are the same with those after standard association of preoperative uterovaginal brachytherapy and surgery.

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Keywords

14 young women
 
actuarial specific survival rates
 
carcinoma
 
local recurrence
 
mean follow-up 75 months
 
ovarian function
 
Ovarian transposition
 
post-operative prophylactic vaginal brachytherapy
 
post-operative vaginal brachytherapy
 
postoperative vaginal brachytherapy
 
preoperative uterovaginal brachytherapy
 
radical hysterectomy
 
small uterine cervix cancer
 
small volume uterine cervix cancer
 
specific survival
 
surgical time
 
unfavourable prognostic factors
 
young women
 

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