Antiretroviral medications and HIV.
ABSTRACT Since 1996 the use of combination antiretroviral treatment including protease inhibitors has dramatically improved the prognosis for many people with HIV. However, antiretroviral medications are associated with significant side effects.
To outline some of the important side effects of antiretroviral medications and strategies for managing complications.
Awareness of potential problems, careful prescribing behaviour and close monitoring can reduce the impact of many side effects of antiretroviral medication. Identification and management of side effects may also assist in improving adherence to treatment.
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ABSTRACT: This paper compares rates of current depression among men attending high-HIV-caseload general practices in New South Wales and South Australia. Current depression was assessed by the treating general practitioner (GP), using the nine-item Patient Health Questionnaire (PHQ-9), and by patient self-reporting. The study found that GPs, the PHQ-9 screening tool and patients were equally likely to identify current depression. High rates of depression were observed among the men attending general practice, with the highest rates among men with HIV and men who did not identify as either heterosexual or homosexual.Mental Health in Family Medicine 06/2008; 5(2):79-83.
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ABSTRACT: Women are the fastest growing segment of the adult population acquiring HIV, and most women infected with HIV are in their reproductive years. The success of HAART is highly dependent upon the ability and willingness of the individual to adhere to complex antiretroviral regimens. Improved adherence among HIV-infected pregnant women will delay disease progression in the mother and should also reduce HIV transmission to the baby. Modified directly observed therapy (MDOT), may benefit this population. MDOT has been shown to be an acceptable and feasible intervention among HIV substance users; however, no-one has yet evaluated the use of MDOT in pregnant and postpartum women. Based on semi-structured interviews with 17 Latina women with HIV infection, we explored women's adherence patterns and barriers to adherence and their perceptions of a hypothetical MDOT program. The vast majority of women positively appraised the MDOT program as an effective means to increase and reinforce adherence to demanding drug regimens. Respondents cited the face-to-face contact, the supportive nature of the relationship, and the practical approach of the program as the primary reasons for the effectiveness of MDOT. Results indicate that MDOT could be an acceptable intervention for pregnant and postpartum Latina women to improve adherence to HAART.Women & Health 02/2006; 44(4):61-77. · 1.00 Impact Factor