Spider-mite allergy and asthma in fruit growers
ABSTRACT Asthma and allergic diseases caused by domestic mites such as house dust mites and storage mites are major health problems worldwide. In contrast to domestic mites, spider mites are outdoor phytophagous mites causing significant damage to fruit leaves throughout the world. After several case reports of spider mite-induced asthma and allergy, cross-sectional surveys have demonstrated that spider mites are important allergens in the development of asthma and rhinitis in fruit farmers. Interestingly, epidemiological surveys have also demonstrated that spider mites are common sensitizing allergens that are related to the prevalence of asthma and rhinitis, even in the non-farming population exposed to spider mites. Protein analysis has demonstrated that crude extracts derived from spider mites contain several major allergens, and that N-terminal amino acid sequencing of the major allergens is not homologous with any previously characterized domestic mite allergens, suggesting that major allergens derived from spider mites are unique in terms of cross-reactivity to domestic mites. Taken together, these findings suggest that spider mites are important allergens in the development of asthma among the exposed non-farming population as well as among fruit farmers themselves, and that allergens derived from spider mites may be novel allergens.
- SourceAvailable from: digitaljournals.org[Show abstract] [Hide abstract]
ABSTRACT: The prevalence of allergic rhinitis and asthma has recently increased in Korea, and both conditions are recognized as major chronic respiratory diseases requiring active intervention. The prevalence of rhinitis among asthmatic patients is high, ranging from 60 to 80%, and could seriously affect asthma severity and outcome. We suggest that allergic rhinitis should be properly evaluated in asthmatic patients to achieve better asthma control.Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand 11/2008; 27(2-3):167-71. · 1.26 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Recent studies among farm workers suggest that excessive pesticide use as well as biological factors such as outdoor mites may be responsible for asthma symptoms experienced by workers. Grape farms, in contrast to fruit farms, have not been previously investigated for occupational respiratory allergy to spider mites. A cross-sectional study was conducted on 207 workers employed in nine table grape farms, investigating allergic sensitisation to common inhalants and occupational allergens. Common work-related symptoms included wheezing (26%), rhino-conjunctivitis (24%), urticaria/skin symptoms (15%) and doctor diagnosed asthma present in 9% of subjects with work-related symptoms. These work-related symptoms were significantly higher (p<0.001) in the orchards compared to the stores. The highest prevalence of positive skin prick tests was observed to spider mite (T. urticae) with 23%, followed by HDM (D. Pteronyssinus) with 16% and cockroach (B. germanica) with 12%. This study has demonstrated that spider mites such as Tetranychus urticae may be important outdoor allergen responsible for allergic symptoms among table grape farm workers in the Western Cape province of South Africa.Current Allergy and Clinical Immunology 01/2002; 15(4):174-177. DOI:10.13140/2.1.3403.3284 · 0.15 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: To describe the latest developments in the field of occupational asthma and occupational rhinitis in 2001 and 2002. Several surveillance programs of occupational diseases, such as Observatoire National des Asthmes Professionnels in France, Surveillance of work-related and Occupational Respiratory Diseases in South Africa (SORDSA), Surveillance of Work-related and Occupational Respiratory Diseases (SWORD) in UK, have reported on the frequency of occupational asthma. The causative agents were mainly flour, isocyanates and latex. The common methods of diagnosis - questionnaires, cutaneous tests, Peak Expiratory Flow Rate (PEFR), bronchial hyperresponsiveness - still create controversy. In addition, the specific bronchial challenge, the classical gold standard of diagnosis, has its limitations since it cannot be performed in every case. Other methods have been assessed as inflammatory markers in induced sputum. Occupational rhinitis appears to be a poorly diagnosed condition. Further studies are expected to explore the effect of environmental control and medical surveillance. The key to successful management of occupational asthma and occupational rhinitis may be prospective surveillance of the occurrence of specific IgE antibodies before the onset of allergic symptoms.Current Opinion in Allergy and Clinical Immunology 05/2003; 3(2):95-100. DOI:10.1097/01.all.0000064772.57552.27 · 3.66 Impact Factor