Pastore G, Mosso ML, Magnani C, Luzzatto L, Bianchi M, Terracini BPhysical impairment and social life goals among adult long-term survivors of childhood cancer: a population-based study from the childhood cancer registry of Piedmont, Italy. Tumori 87: 372-378
The study describes the health status and the attainment of life goals in the adult survivors of childhood cancer recorded at the Childhood Cancer Registry of Piedmont.
A postal questionnaire was sent to the general practitioner of the 690 cases born before 1976 and alive in 1991 after at least 5 years from diagnosis. The answer was received for 485 (72.9%) included in the analyses. Items in the questionnaire were: sequelae related to cancer and its treatment, health-related quality of life (according to Bloom's criteria), educational level attained, and employment status.
Vital and marital status were obtained for all 690 cases at the offices of the town of residence. No medical condition was reported for 309 cases (63.7%). The overall proportion with a high school or university education was compared to corresponding figures for Piedmont in 1991, adjusted by age, and was as high as in the general population. Similar results are observed for occupation. Patients of both genders were married less than expected. Patients with leukemia (112 cases), non-Hodgkin's lymphoma (34) or Hodgkin's lymphoma (52) were reported to have the highest quality of life. In contrast, patients with tumors of the central nervous system (151) had the highest frequency of sequelae and the lowest score for health-related quality of life. They-also presented the lowest educational achievement, the lowest proportion of employment and, among males, the lowest frequency of marriage.
Our study shows a good social adjustment of adult survivors from childhood cancer, with the exception of central nervous system tumors. From the methodologic point of view, the present study shows the feasibility of surveillance surveys on health-related quality of life with the contribution of general practitioners.
"There are, however, some references within the international childhood cancer literature to cancer-related impairment experience in a life-course context. This work has consistently found that people who had experienced childhood cancer were as a whole less likely to marry (for example, Byrne et al. 1989; Rauck et al. 1999; Pastore et al. 2001; Frobisher et al. 2007). In relation to childhood cancer, it has been suggested that fertility concerns might impact relationship formation; whilst analysis of the British Childhood Cancer Survivor Study (Frobisher et al. 2007) did not support this there is clear evidence of the value of fertility information and support for cancer survivor men and women (Crawshaw 2013). "
[Show abstract][Hide abstract] ABSTRACT: Partnerships and parenthood can have important effects on economic, social and psychological well-being. We provide new long-term analysis of how disability affects both parental status and partnerships. Analysis of the new Life Opportunities Survey, which is based on social model approaches, demonstrates that disabled people are more likely than non-disabled people to face disadvantages in terms of family formation. Disabled people are more likely to remain single over time, although there is less evidence for any differences in rates of relationship breakdown for those who enter them. Allied to these conclusions, disabled adults are less likely to form households where there are dependent children. These conclusions are supported by longitudinal results from the British Household Panel Survey.
Disability & Society 04/2014; 29(4). DOI:10.1080/09687599.2013.831745 · 0.73 Impact Factor
"USA Mixed XS 6Á16 1Á6 P, S, T R/M, PN  Italy Mixed L M024 ]5 R P N  Austria Mixed M M023 M014 S PN  USA Mixed XS 11Á21 M01.5 S M  Finland Leukemia XS M 017 M017 S M  Finland Leukemia XS M 020 M08 S M  USA Brain tumour S 6Á18 2Á5 P , S , T P N  "
[Show abstract][Hide abstract] ABSTRACT: The aim was to investigate whether there are any positive consequences of childhood cancer. Studies published 1990-2005 reporting survivors' descriptions of positive consequences of childhood cancer were identified through a search in the databases CINAHL, PsycINFO, and PubMed. According to a manifest content analysis, positive consequences were referred to three themes: life values, relations to others, and relation to self. A second search in the same databases was conducted to identify studies investigating whether survivors of childhood cancer differ from comparison groups with regard to variables assigned to these themes. In these studies, no conclusions about positive consequences with regard to the theme life values can be drawn, as only one study was identified. In addition, only a small minority of findings from comparative studies indicate that childhood cancer has any positive consequences with regard to relations to others and relation to self. A majority of the results indicate that survivors do not differ from comparison groups, whereas some findings highlight that friendship and marital status are areas of concern, and parenthood and sexuality are areas of potential concern. It is recommended that survivors of childhood cancer are followed up by a multi-professional team, focusing not only on the survivors' health status but also on relations to family, friends, and partners.
"Another study also found that the educational level of survivors of non-CNS tumours exceeded that of the general population (Pastore et al, 2001), and childhood cancer survivors have been described as more mature, with greater appreciation of parental support, than healthy controls (Maggiolini et al, 2000). Our study confirms previous findings that only the survivors of childhood CNS tumours experience problems in achieving longterm educational outcomes (Kelaghan et al, 1988; Haupt et al, 1994; Pastore et al, 2001). The study of Langeveld et al (2003) accorded with our findings but lacked statistical power, which might explain the authors' more pessimistic conclusions of reduced educational attainment among cancer survivors in general, as also in another study (Teta et al, 1986). "
[Show abstract][Hide abstract] ABSTRACT: We identified 2384 patients in the Danish Cancer Register in whom cancer had been diagnosed in 1960-1996 before they reached the age of 20 and compared them with 53 143 sex- and age-matched controls identified from the Register of Population Statistics. Complete education records and demographic and socioeconomic information for the period 1980-2000 were obtained for both cohorts from Statistics Denmark. The rate ratio (RR) for educational attainment was estimated by discrete-time Cox regression analyses. An overall reduction in attaining basic education was found (RR, 0.90; 95% confidence interval, 0.83-0.96). Female survivors of central nervous system (CNS) tumours showed the largest educational deficit (RR, 0.55; 95% confidence interval, 0.37-0.82). Non-CNS tumour survivors attained education as controls at most levels. When the analyses were conditioned on completion of youth education, further educational attainment was not reduced for any group of survivors. These findings confirm that only survivors of CNS tumours in childhood experience significant educational deficits. The deficit was mainly seen among persons whose tumour was diagnosed before they reached the level of secondary education.
British Journal of Cancer 09/2004; 91(5):923-8. DOI:10.1038/sj.bjc.6602085 · 4.84 Impact Factor
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