Metabolism of dietary essential fatty acids and their conversion to long-chain polyunsaturated metabolites

Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4474, USA.
Journal of the American Veterinary Medical Association (Impact Factor: 1.56). 07/2002; 220(11):1621-6. DOI: 10.2460/javma.2002.220.1621
Source: PubMed
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    ABSTRACT: Fish oil omega-3 fatty acids, mainly eicosapentaenoic acid and docosahexaenoic acid, are used in the management of several diseases in companion animal medicine, many of which are inflammatory in nature. This review describes metabolic differences among omega-3 fatty acids and outlines potential adverse effects that may occur with their supplementation in dogs and cats with a special focus on omega-3 fatty acids from fish oil. Important potential adverse effects of omega-3 fatty acid supplementation include altered platelet function, gastrointestinal adverse effects, detrimental effects on wound healing, lipid peroxidation, potential for nutrient excess and toxin exposure, weight gain, altered immune function, effects on glycemic control and insulin sensitivity, and nutrient-drug interactions.
    Journal of Veterinary Internal Medicine 01/2013; 27(2). DOI:10.1111/jvim.12033 · 1.88 Impact Factor

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