Nail pigmentation caused by hydroxyurea: Report of 9 cases
Department of Dermatology, Ospedale S. Giovanni de Dio, University of Cagliari, Via Ospedale 54, 09124-Cagliari, Italy. Journal of the American Academy of Dermatology
(Impact Factor: 4.45).
08/2002; 47(1):146-7. DOI: 10.1067/mjd.2002.120910
We report a series of 9 patients, 6 men and 3 women, who presented nail hyperpigmentation arising between 6 and 24 months from the start of hydroxyurea therapy. The most commonly observed clinical pattern was that of longitudinal melanonychia. In only 1 patient, who was affected in all 20 nails, we observed longitudinal melanonychia, diffuse melanonychia, and hyperpigmentation of the skin.
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