Article

Perilymphatic pressure measurement in Meniere's disease.

Department of Otorhinolaryngology, Fondation Adolphe de Rothschild, Paris, France.
The Annals of otology, rhinology, and laryngology (impact factor: 1.05). 08/2002; 111(7 Pt 1):653-6. pp.653-6
Source: PubMed

ABSTRACT The aim of this study was to evaluate the perilymphatic pressure, by means of the MMS-10 Tympanic Displacement Analyzer (TDA), in patients with Meniere's disease (MD). Measurements were performed in 37 patients with MD and in 14 normal-hearing subjects. Data were collected from 3 groups: healthy ears of normal-hearing subjects, unaffected ears of patients with MD, and affected ears of patients with MD. Analysis of the results obtained with the TDA showed no significant differences between the 3 groups. Several hypotheses could explain this lack of difference: 1) perhaps indirect measurement of perilymphatic pressure with the TDA is not relevant; 2) perhaps hyperpressure of the inner ear is not the physiological basis for the clinical triad of MD; or 3) perhaps endolymphatic hydrops does not produce changes in perilymphatic pressure. The results of this series indicate that the TDA is not useful in the evaluation of patients with MD.

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Keywords

14 normal-hearing subjects
 
3 groups
 
37 patients
 
ears
 
healthy ears
 
hypotheses
 
inner ear
 
MD
 
Measurements
 
Meniere's disease
 
MMS-10 Tympanic Displacement Analyzer
 
normal-hearing subjects
 
patients
 
perilymphatic pressure
 
physiological basis
 
unaffected ears
 

Denis Ayache