Influence of replacement schedule and care regimen on patient comfort and satisfaction with daily wear frequent-replacement contact lenses.
ABSTRACT This study examines what effects replacement schedule and care regimen have on overall patient satisfaction with daily wear frequent-replacement contact lenses.
Over 3000 patients were recruited from 313 ophthalmologic practices in France to participate in a 1-month prospective observational clinical study. Subjects included 2108 experienced and 957 novice users of the predominantly prescribed soft contact lenses and care systems in France. All subjects were required to use ACUVUE 2 (Vistakon, Jacksonville, FL) brand contact lenses, replaced once every 2 weeks, and using COMPLETE brand multipurpose solution (Allergan, Irvine, CA) during the study. Practitioners assessed lens fit, and refractive and ocular physiological status. Subjects were surveyed about various subjective attributes at the baseline examination and at the end of the study.
Patient satisfaction with the test lenses and care system was found to be excellent for the majority of patients, as evidenced by high subjective satisfaction ratings and the desire of approximately 9 of 10 subjects to continue using the test products after completing the study. Significant improvements were noted with the test lenses and solution compared to previous lenses and solutions for overall satisfaction and comfort variables.
Replacing lenses once every 2 weeks combined with a multipurpose care system incorporating ingredients designed for lens conditioning contributed to significant improvements in lens wearing comfort. Thus, lens replacement frequency and lens-and-solution compatibility should be considered in addition to lens material and design when prescribing contact lenses for new or existing wearers.
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ABSTRACT: Since the initial development of silicone hydrogels, many modifications to the bulk and surface properties of the lenses have been undertaken to improve the wettability and comfort of the lenses. Recently, manufacturers have incorporated various "wetting agents" or surface-active agents into the blister packaging solutions (BPSs) of the lenses to improve initial comfort of the lens on eye. The purpose of this study was to measure and compare the pH, surface tension (ST), viscosity, and osmolality of BPSs for a variety of silicone hydrogel and polyHEMA-based hydrogel lenses. In addition, two saline solutions were tested for comparison purposes. The pH, osmolality, ST, and viscosity were measured for the BPSs for lotrafilcon B and lotrafilcon A and lotrafilcon B with a "modified BPS" (m-lotrafilcon A, m-lotrafilcon B) (CIBA Vision, Duluth, GA); balafilcon A (Bausch & Lomb, Rochester, NY); galyfilcon A, senofilcon A, and narafilcon A (Johnson & Johnson, Jacksonville, FL); and comfilcon A and enfilcon A (CooperVision, Pleasanton, CA) and BPSs from two conventional polyHEMA-based materials-etafilcon A (Johnson & Johnson) and omafilcon A (CooperVision). The two saline solutions tested were Unisol (Alcon, Fort Worth, TX) and Softwear Saline (CIBA Vision). The pH results for the two saline solutions and all BPSs remained in the pH range of tears (6.6-7.8). The ST of the modified BPS was significantly lower (p < 0.01) than the original non-modified BPS. Viscosity measurements ranged between 0.90 and 1.00 cP for all BPSs and saline solutions, except for the modified BPS, which had significantly higher viscosities (p < 0.001). Osmolality measurements were not significantly different (p > 0.05) between BPSs made by the same manufacturer but were significantly different compared with BPSs made by different manufacturers (p < 0.05). The incorporation of wetting agents and surfactants into BPSs does alter the physical properties of the BPSs, which may have clinical implications regarding initial in-eye comfort.Optometry and vision science: official publication of the American Academy of Optometry 12/2010; 88(4):493-501. · 1.53 Impact Factor