Transcutaneous Bilirubinometry and Diagnostic Tests: "The Right Job for the Tool"

Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109-0254, USA.
PEDIATRICS (Impact Factor: 5.47). 09/2002; 110(2 Pt 1):407-8. DOI: 10.1542/peds.110.2.407
Source: PubMed
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    PEDIATRICS 05/2003; 111(4 Pt 1):919-20; author reply 919-20. DOI:10.1542/peds.111.4.919 · 5.47 Impact Factor
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    ABSTRACT: A prospective observational study was conducted on 212 neonates born between 24 and 42 weeks of gestation who required blood sampling to determine total serum bilirubin (TSB) in the first week of life, prior to phototherapy. The transcutaneous bilirubin (TcB) measurements were performed on the infant's forehead using BiliCheck within +/-30 min of a blood sample being drawn. There was significant (r = 0.78) correlation between bilirubin levels obtained transcutaneously and those measured in the infant's blood. The correlation was not affected by birth weight and was dependent on the bilirubin levels. The negative nonsignificant correlation appears when TSB levels are greater than 11 mg/dl. Thus, TcB measurements can accurately predict TSB values lower than 11 mg/dl in a multiracial preterm and term neonatal population.
    Biology of the Neonate 02/2004; 85(1):21-5. DOI:10.1159/000074953 · 1.74 Impact Factor
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    ABSTRACT: To evaluate performance of the Minolta JM-103 Jaundice Meter (JM) as a predictor of total serum bilirubin (TSB) in outpatient neonates during the first week postnatal, and to estimate the number of TSB determinations that might be avoided in clinical use. In neonates evaluated posthospital discharge, JM and TSB results were compared using linear regression and a Bland-Altman plot, and predictive indices were calculated for various JM cutoff values. Utilizing the 2004 American Academy of Pediatrics (AAP) guidelines, the ability of JM to predict risk zone status was determined. Overall correlation between JM and TSB was 0.77 (p<0.001; n=121). When TSB was >17 mg/dl, a cutoff value for JM of 13 mg/dl had a sensitivity of 1.0, and 50% of TSB determinations would be avoided. JM may facilitate outpatient management of hyperbilirubinemia by reducing the number of TSB determinations required; however, it does not provide a reliable substitute for laboratory measurement of TSB.
    Journal of Perinatology 07/2005; 25(7):486-90. DOI:10.1038/ · 2.07 Impact Factor
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