Article

Physicians' propensity to offer genetic testing for Alzheimer's disease: results from a survey.

Department of Biostatistics and Research Epidemiology, Henry Ford Health Sciences Center, Johns Hopkins University School of Mediicne, Baltimore, MD, USA.
Genetics in Medicine (impact factor: 4.76). 4(4):297-303. DOI:10.109700125817-200207000-00008 pp.297-303
Source: PubMed

ABSTRACT Examine physician knowledge, preferences, and use of genetic tests for Alzheimer's disease (AD).
Survey of 426 community-based physicians treating AD patients.
Majority gave inaccurate estimates of AD risk. Medical specialty predicted appropriate use of current tests. Recommending substances to prevent memory loss was related to acceptance of error-free tests. High patient loads and familiarity with genetic tests predicted lower tolerance for test error.
Physicians do not endorse indiscriminate genetic susceptibility testing for AD. However, insufficient knowledge of disease risk, etiology, genetic susceptibility, and use of existing tests indicated a need for further physician education in this area.

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Keywords

426 community-based physicians
 
AD patients
 
AD risk
 
appropriate use
 
current tests
 
disease risk
 
error-free tests
 
genetic susceptibility
 
genetic susceptibility testing
 
genetic tests
 
insufficient knowledge
 
lower tolerance
 
Medical specialty
 
patient loads
 
physician education
 
Physicians
 
preferences
 
Recommending substances
 
tests