Article

Hepatofugal portal flow in advanced liver cirrhosis with spontaneous portosystemic shunts: effects on parenchymal hepatic enhancement at dual-phase helical CT.

Department of Radiology, Université René Descartes, Hôpital Cochin, 27 rue du Fg Saint Jacques, 75679 Paris Cedex 14, France.
Abdominal Imaging (impact factor: 1.73). 27(5):536-40. DOI:10.1007/s00261-001-0095-7 pp.536-40
Source: PubMed

ABSTRACT We investigated whether spontaneous hepatofugal portal flow in advanced cirrhosis affects hepatic enhancement on dual-phase helical computed tomography.
Fifteen patients with hepatofugal portal flow on Doppler sonography and angiography (group 1) and 15 age- and sex-matched patients with hepatopetal portal flow (control; group 2) underwent dual-phase helical computed tomography. Vascular and liver attenuation values were measured on unenhanced scans and scans obtained during hepatic arterial (HAP; 25 s) and portal venous (PVP; 70 s) phases.
Portal vein enhancement was lower during PVP in group 1 than in group 2 ( p < 0.0001). Liver enhancement was higher during HAP and lower and delayed during PVP in group 1 versus group 2 ( p < 0.0001).
In hepatofugal portal flow, liver enhancement is increased during HAP and compensating for decreased and delayed liver enhancement during PVP, resulting in potential decreased hypervascular tumor conspicuity.

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Keywords

angiography
 
cirrhosis
 
Doppler sonography
 
dual-phase helical computed tomography
 
group 1
 
group 2
 
HAP
 
hepatic arterial
 
hepatic enhancement
 
hepatofugal portal flow
 
hepatopetal portal flow
 
hypervascular tumor conspicuity
 
liver enhancement
 
Portal vein enhancement
 
portal venous
 
PVP
 
scans
 
sex-matched patients
 
spontaneous hepatofugal portal flow
 
unenhanced scans
 

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