Article

Predictors of effective bilateral subthalamic nucleus stimulation for PD.

Department of Clinical and Biological Neurosciences, Joseph Fourier University, Grenoble, France.
Neurology (impact factor: 8.31). 10/2002; 59(6):932-4. pp.932-4
Source: PubMed

ABSTRACT To identify factors predictive of effective bilateral subthalamic nucleus (STN) stimulation for PD with severe motor complications, pre- and postoperative Unified PD Rating Scale (UPDRS) scores were analyzed in a series of 54 patients who received bilateral STN stimulation. Younger age and levodopa responsiveness predict a favorable response to bilateral STN stimulation. For individual PD symptoms, those that improve with a suprathreshold dose levodopa challenge are likely to improve with stimulation.

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Keywords

bilateral STN stimulation
 
effective bilateral subthalamic nucleus
 
factors predictive
 
individual PD symptoms
 
levodopa responsiveness
 
postoperative Unified PD Rating Scale
 
pre-
 
suprathreshold dose levodopa challenge
 
Younger age
 

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