Some unusual complications of malignancies: case 1. Spontaneous rupture of hepatocellular carcinoma demonstrated by contrast-enhanced sonography.

Veterans General Hospital-Taipei and School of Medicine and Institute of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan.
Journal of Clinical Oncology (Impact Factor: 18.43). 11/2002; 20(19):4108-11.
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    • "Rupture of HCC is confirmed by performing abdominal paracentesis, and the fluid shows blood-stained ascites. However, an imaging study such as ultrasonography or CT can demonstrate the extent of blood loss, the severity of the liver cirrhosis, the location of the tumor and the patency of the portal vein [11]. "
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    ABSTRACT: A 57-yr-old woman previously diagnosed with chronic hepatitis B was admitted via the emergency room because she suddenly developed epigastric pain with abdominal distension. On computed tomography (CT), a round enhancing mass was found on the left hepatic lobe with ascites in the peritoneal space. Bloody ascites were found upon tapping the ascites, and this led to the diagnosis of ruptured hepatocellular carcinoma (HCC). The patient was immediately treated with transcatheter arterial chemoembolization (TACE) including 50 mg of adriamycin and 10 mL of lipiodol, and then we performed left lateral segmentectomy 20 days later. To prevent recurrence of HCC by any micrometastasis, the patient subsequently received 8 cycles of adjuvant systemic chemotherapy (a regimen of epirubicin (50 mg/m(2)), cisplatin (60 mg/m(2)) and 5-fluorouracil (200 mg/m(2))) at monthly intervals. After this, the patient has been regularly followed up and she shows no signs of tumor recurrence 7 years later. This case suggests that surgical resection and subsequent adjuvant systemic chemotherapy with using an ECF regimen may provide long-term survival for patients ruptured HCC.
    The Korean Journal of Internal Medicine 04/2009; 24(1):63-7. DOI:10.3904/kjim.2009.24.1.63 · 1.43 Impact Factor
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    ABSTRACT: Nonbacterial thrombotic endocarditis (NBTE) is a rather frequent neoplasic complication, most often occurring in adenocarcinomas of the lung and pancreas. The most frequent clinical manifestation is one of multiple cerebral infarcts, but other ischaemic events can occur. Diagnosis is frequently missed on transthoracic ultrasound, making transoesophagic ultrasound a more reliable diagnostic tool. We present a case of NBTE associated with lung adenocarcinoma.
    Clinical and Translational Oncology 12/2007; 9(11):744-6. DOI:10.1007/s12094-007-0133-1 · 2.08 Impact Factor


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