Antioxidant Properties of Several Medicinal Mushrooms

Department of Food Science, National Chung-Hsing University, 250 Kuokuang Road, Taichung 402, Taiwan, Republic of China.
Journal of Agricultural and Food Chemistry (Impact Factor: 2.91). 10/2002; 50(21):6072-7. DOI: 10.1021/jf0201273
Source: PubMed


Three species of medicinal mushrooms are commercially available in Taiwan, namely, Ganoderma lucidum (Ling-chih), Ganoderma tsugae (Sung-shan-ling-chih), and Coriolus versicolor (Yun-chih). Methanolic extracts were prepared from these medicinal mushrooms and their antioxidant properties studied. At 0.6 mg/mL, G. lucidum, G. lucidum antler, and G. tsugae showed an excellent antioxidant activity (2.30-6.41% of lipid peroxidation), whereas C. versicolor showed only 58.56%. At 4 mg/mL, reducing powers were in the order G. tsugae (2.38) approximately G. lucidum antler (2.28) > G. lucidum (1.62) > C. versicolor (0.79). At 0.64 mg/mL, scavenging effects on the 1,1-diphenyl-2-picrylhydrazyl radical were 67.6-74.4% for Ganoderma and 24.6% for C. versicolor. The scavenging effect of methanolic extracts from G. lucidum and G. lucidum antler on hydroxyl radical was the highest (51.2 and 52.6%) at 16 mg/mL, respectively. At 2.4 mg/mL, chelating effects on ferrous ion were in the order G. lucidum antler (67.7%) > G. lucidum (55.5%) > G. tsugae (44.8%) > C. versicolor (13.2%). Total phenols were the major naturally occurring antioxidant components found in methanolic extracts from medicinal mushrooms. Overall, G. lucidum and G. tsugae were higher in antioxidant activity, reducing power, scavenging and chelating abilities, and total phenol content.

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Available from: Jeng-Leun Mau, Feb 13, 2014
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    • "Modern pharmaceutical research shows that G. lucidum polysaccharide (GLP) has several physiological and health effects including strong antioxidant activities [18]. In addition its therapeutic effects, the Ethanolic extracts from G. lucidum and G. tsugae also possess antioxidant abilities [19]. Various components of G. lucidum, in particular polysaccharides and triterpenoids, show high antioxidant activity in vitro [20] [21] [22] [23] [24] [25]. "
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    ABSTRACT: To study the isolation, structural characterization and antioxidant activities of polysaccharide from the medicinal mushroom G.lucidum. In this study structural characterization of Ganoderma lucidum polysaccharides was conducted by Fourier Transform Infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) analyses. Antioxidant activities of Ganoderma lucidum polysaccharides was measured by 1,1–diphenyl–2–icryl-hydrazyl (DPPH-), Hydroxyl radical scavenging assay (HO-), superoxide anion (O-) radical scavenging assay and Ferrous ion (Fe 2+) chelating assay. Scavenging effect of G. lucidum polysaccharides and ascorbic acid on the DPPH radical scavenging, Hydroxyl radical scavenging, superoxide anion radical scavenging and Ferrous ion (Fe 2+) chelating radical scavenging-dependently increased and was 30.45% and 85.40%, 35.70% and 90.50%, 49.68% and 90.10%, 32.69% and 80.26% at the dose of 4 mg/ml respectively. The FT-IR spectra revealed the general characteristic absorbance peaks of the GLP. The SEM image demonstrated surface features of the GLP. This study suggests that the Ganoderma lucidum polysaccharides could potentially be used as natural antioxidants.
    • "High levels of inhibition of lipid peroxidation limit free radical formation, which has an active role in the development of diseases. Various studies on mushrooms and other plant extracts also demonstrated that methanolic extracts possess high lipid peroxidation inhibition capacity (Dinis et al., 1994; Young and Woodside, 2001; Mau et al., 2002). In the present study, the level of inhibition of lipid peroxidation by millipede extracts was higher than that of ascorbic acid, denoting that the extracts scavenge free radicals as a primary antioxidant. "
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    ABSTRACT: Along with plant sources, arthropods (such as millipedes) are also known for their antioxidant activities that can help combat human ailments. Therefore, methanol extracts of males and females of two endemic giant pill-millipedes of the Western Ghats (Arthrosphaera fumosa Pocock and Arthrosphaera magna Attems) were evaluated for antioxidant potential. The bioactive principles and activities assessed were total phenolics, total antioxidant activity, 2,2-diphenyl-1-picrylhydrazyl or DPPH radical scavenging, ferrous ion chelation, reducing power and hydrogen peroxidase scavenging. Significant differences were shown between the two species, the sexes and the sexes within millipede species in total antioxidant activity, DPPH radical scavenging and ferrous ion chelation. Total phenolics and EC50 of DPPH radical scavenging activity differed significantly only between species and the sexes. This study clearly demonstrated that the antioxidant capacity of the methanol extract of Arthrosphaera spp. is comparable to the ascorbic acid standard and possesses potential scavenging ability against reactive oxygen species generated during oxidative stress.
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    • "A number of medicinal benefits have been ascribed to consumption of mushrooms including the treatment of chronic and degenerative diseases, obesity and cardiovascular disorders (Kavishree et al., 2009; Ribeiro et al., 2008). Likewise, a wide spectrum of biological activities of mushroom species/taxa such as anti-tumor, anti-microbial and anti-oxidant has been investigated (Mau et al., 2002; Wasser and Weis, 1999; Barros et al., 2007; Lindequist et al., 2005). "

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