Article

Proteomic analysis in the neurosciences.

Neurological Surgery, University of Washington School of Medicine, Seattle, Washington 98195-6470, USA.
Molecular &amp Cellular Proteomics (impact factor: 7.4). 09/2002; 1(8):553-60. pp.553-60
Source: PubMed

ABSTRACT Proteomics is a field of study directed toward providing a comprehensive view of the characteristics and activity of every cellular protein. Rapid innovations in the core technologies required to characterize proteins on a global scale are poised to bring about a comprehensive understanding of how dynamic changes in protein expression, post-translational modification, and function affect complex signaling and regulatory networks. These advances have significant implications for understanding the multitude of pathways that govern behavior and cognition and the response of the nervous system to injury and disease.

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Keywords

cellular protein
 
comprehensive understanding
 
comprehensive view
 
govern behavior
 
multitude
 
nervous system
 
post-translational modification
 
protein expression
 
proteins
 
Rapid innovations
 
regulatory networks
 

Richard S Morrison