Twin and family studies of the human electroencephalogram: a review and a meta-analysis.

Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands.
Biological Psychology (Impact Factor: 3.47). 11/2002; 61(1-2):111-38. DOI: 10.1016/S0301-0511(02)00055-8
Source: PubMed

ABSTRACT Electrophysiological measures may be useful markers of the genetic underpinnings of complex behavior and psychopathology. Twin and family studies have been used to estimate the genetic contribution to the individual differences in a variety of electrophysiological measures. These studies are briefly reviewed here and published twin correlations from a number of studies with comparable methodology were selected for structural equation meta-analyses. For electroencephalographic (EEG) alpha power (11 twin groups) the heritability estimates in each of the single studies were high (averaged 79%), but it was not possible to equate the twin correlations across studies in the meta-analysis. In contrast, combining the data on alpha peak frequency (five twin groups) revealed a 'meta'-heritability of 81% (95% CI: 76-84%). Aggregating the twin correlations of five twin studies on the P300, the estimated meta-heritability is 60% (95% CI: 54-65%) for P300 amplitude and 51% (95% CI: 43-58%) for P300 latency. It is concluded that genomic variation contributes significantly to individual differences in all EEG and event related potential (ERP) measures studied to date.

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    Annals of Neurosciences 10/2014; 21(4):144-149. DOI:10.5214/ans.0972.7531.210406
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    ABSTRACT: The purpose of this paper is to identify the cerebral electrical activity features in men with a high or low α-frequency background while performing the alternate finger movements. A test group consisting of 104 healthy men from the ages of 19 to 21 was divided into two groups according to the magnitude of their individual α- frequency (ІАF) median –groups with high (n = 53, IAF ≥10,04 Hz) and low (n = 51, IAF ≤10,03 Hz) levels of ІАF. Changes in power and the coherence of the EEG oscillations during the alternate finger movements as well as intergroup differences were evaluated. Men with high a IAF are distinguished by higher rates of speed and accuracy in terms of their sensory-motor response. The role of inhibitory neural processes increases in the case of men whose frequencies are low. The implementation of alternating finger movements in male groups is accompanied by a decrease in the coherence of θ-, α1-, α3- EEG oscillations in the cortex in general, β- and γ-activity - in the rear temporal and occipital areas. In the frontal and central lobes of α2-, β- and γ- ranges an increase in EEG coherence fuctuations was observed. The power of θ-, α- and β1- waves, especially in the posterior cortex areas, decreases. A larger degree of low-frequency fuctuations in EEG power can be observed in the frontal area. Thus, more economical brain processes providing the processing of any sensory or motor information in men with a high IAF determine higher levels of the speed and accuracy of their sensorimotor responses. Men with a low IAF have lower ductility but a higher voltage of brain processes correlated with a decrease in the sensorimotor response of speed capabilities increasing the role of inhibitory effects.
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    Schizophrenia Research 11/2014; 160(1-3). DOI:10.1016/j.schres.2014.10.042 · 4.43 Impact Factor


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