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    • "Ninety-two patients referred to participate in a cardiac rehabilitation program participated in the study. Inclusion criteria were (a) history of coronary artery disease diagnosed by American Heart Association standard criteria [21] "
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    ABSTRACT: Background: We tested the hypothesis that high intensity interval training (HIIT) would be more effective than moderate intensity continuous training (MIT) to improve newly emerged markers of cardiorespiratory fitness in coronary heart disease (CHD) patients, as the relationship between ventilation and carbon dioxide production (VE/VCO2 slope), oxygen uptake efficiency slope (OUES), and oxygen pulse (O2P). Methods: Seventy-one patients with optimized treatment were randomly assigned into HIIT (n = 23, age = 56 ± 12 years), MIT (n = 24, age = 62 ± 12 years), or nonexercise control group (CG) (n = 24, age = 64 ± 12 years). MIT performed 30 min of continuous aerobic exercise at 70-75% of maximal heart rate (HRmax), and HIIT performed 30 min sessions split in 2 min alternate bouts at 60%/90% HRmax (3 times/week for 16 weeks). Results: No differences among groups (before versus after) were found for VE/VCO2 slope or OUES (P > 0.05). After training the O2P slope increased in HIIT (22%, P < 0.05) but not in MIT (2%, P > 0.05), while decreased in CG (-20%, P < 0.05) becoming lower versus HIIT (P = 0.03). Conclusion: HIIT was more effective than MIT for improving O2P slope in CHD patients, while VE/VCO2 slope and OUES were similarly improved by aerobic training regimens versus controls.
    02/2015; 2015:1-8. DOI:10.1155/2015/192479
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    • "Compared to a simple exercise electrocardiography testing (XECG), perfusion imaging with 201Thallium or 99mTechnetium-sestamibi raises sensitivity, but prognostic value is less established [119]. Perfusion imaging is particularly useful when the resting ECG is abnormal, specifically in women because of false positive results on XECG [120]. In symptomatic patients who have had prior revascularization, reversible areas of ischemia may be quantified and localized to specific areas of the myocardium [121]. "
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    ABSTRACT: Inflammatory mediators appear to be the most intriguing yet confusing subject, regarding the management of patients with acute coronary syndromes (ACS). The current inflammatory concept of atherosclerotic coronary artery disease (CAD) led many investigators to concentrate on systemic markers of inflammation, as well as imaging techniques, which may be helpful in risk stratification and prognosis assessment for cardiovascular events. In this review, we try to depict many of the recently studied markers regarding stable angina (SA), their clinical usefulness, and possible future applications in the field.
    Disease markers 06/2014; 2014:831364. DOI:10.1155/2014/831364 · 1.56 Impact Factor
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    • "Inclusion criteria were as follows: (1) a first-ever stroke as defined by the World Health Organization, (2) stroke less than six months ago, (3) ability to move independently with or without a walking aid and (4) understand and carry out simple instructions. Patients were excluded if they were not medically stable, as described by the American College of Cardiology Foundation/American Heart Association [28]. "
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    ABSTRACT: Objectives to determine the concurrent validity of a physical activity diary for measuring physical activity level and total energy expenditure in hospitalized stroke patients. Method Sixteen stroke patients kept coded activity diaries and wore SenseWear Pro2 multi-sensor activity monitors during daytime hours for one day. A researcher observed the patients and completed a diary. Data from the patients' diaries were compared with observed and measured data to determine total activity (METs*minutes), activity level and total energy expenditure. Results Spearman correlations between the patients' and researchers' diaries revealed a high correlation for total METs*minutes (rs = 0.75, p<0.01) for sedentary (rs = 0.74,p<0.01) and moderate activities (rs = 0.71,p<0.01) and a very high correlation (rs = 0.92, p<0.01) for the total energy expenditure. Comparisons between the patients' diaries and activity monitor data revealed a low correlation (rs 0.29) for total METs*minutes and energy expenditure. Conclusion Coded self-monitoring activity diaries appear feasible as a low-tech alternative to labor-intensive observational diaries for determining sedentary, moderate, and total physical activity and for quantifying energy expenditure in hospitalized stroke patients. Given the poor correlation with objective measurements of physical activity, however, further research is needed to validate its use against a gold-standard measure of physical activity intensity and energy expenditure.
    PLoS ONE 06/2014; 9(6):e98735. DOI:10.1371/journal.pone.0098735 · 3.23 Impact Factor
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