Validity and responsiveness of the national institutes of health chronic prostatitis symptom index.
ABSTRACT The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was validated in a sample of men with longstanding prostatitis but it has not been validated in primary care samples or assessed for responsiveness to change. We assessed its reliability, validity and responsiveness to change in a sample of men with pelvic pain visits to health maintenance organization primary care and urology clinics.
A total of 261 men with recent primary care or urology clinic visits for pelvic pain and no evidence of specific disease completed the NIH-CPSI and validated generic pain and health-related quality of life measures (Graded Chronic Pain Scale, Short-Form 36 and Short-Form 12 scales) in a telephone interview approximately 1 month after the visit, of whom 230 (88%) completed the measures again 3 months later.
Validity was demonstrated for the NIH-CPSI pain and quality of life scales through their moderate correlations with other validated measures of these constructs. The NIH-CPSI total scale but not the subscales showed high internal consistency. The pain, quality of life and total scores were moderately responsive to change (effect size -0.57 to -0.60), but the urinary symptoms scale was less responsive (effect size -0.18).
The NIH-CPSI total score appears to be a valid, reliable, responsive measure of prostatitis symptoms in primary and secondary care patients. The findings support the use of the total score as an outcome measure. It may be useful to supplement it with valid, reliable measures of pain intensity and activity interference.
Article: Depression, anxiety, stress perception, and coping strategies in korean military patients with chronic prostatitis/chronic pelvic pain syndrome.[show abstract] [hide abstract]
ABSTRACT: The objective of this study was to examine the psychological features and coping strategies of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The participants consisted of 55 military personnel suffering from CP/CPPS and 58 military personnel without CP/CPPS symptoms working at the Military Capital Hospital. The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was used to assess CP/CPPS symptoms. The Responses to Hospital Anxiety and Depression (HAD) scale, Social Readjustment Rating Scale, and Global Assessment of Recent Stress (GARS) scale were compared between the two groups. The Weisman Coping Strategy Scale was used to assess coping ability with CP/CPPS. The NIH-CPSI score of the CP/CPPS group was significantly higher than that of the control group for all domains including pain, urinary symptoms, quality of life, and summed score. The Anxiety and Depression domain of the HAD showed significant differences between the two groups. There were no significant differences in the Social Readjustment Rating Scale between the two groups, but the sum of the GARS score was higher in the CP/CPPS group than in the control group. These were correlated with the pain, quality of life, and sum domains of the NIH-CPSI. The Weisman Coping Strategy Scale showed that intellectualization, redefinition, and flexibility were higher in frequency in descending order, and that fatalism, externalization, and self-pity were lower in frequency. The CP/CPPS patients had depression, anxiety, and higher perception of stress. In particular, these were closely related to the pain and quality of life of the patients.Korean journal of urology 09/2012; 53(9):643-8.
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ABSTRACT: Prostate inflammation or infection may increase the risk of prostate cancer. As antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat prostatitis and urinary tract infections (UTIs), our objective was to assess whether their use decreases the risk of prostate cancer. We conducted a case-control study among men with incident prostate cancer (N=65 cases) and without prostate cancer (N=195 controls) at the San Francisco Veteran Affairs medical center (VAMC) between June 1996 and June 2006. Neither total antibiotic use nor total anti-inflammatory use reduces the risk of prostate cancer (P >0.05). Our analysis did not reveal a relation between use of antibiotics or NSAIDs and the risk of prostate cancer.11/2008;
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ABSTRACT: Ôhe term prostatitis is broadly used to describe inflammation of the prostate associated with a variety of lower urinary tract symptoms and signs and sexual dysfunction. Prostatitis poses an international health problem and several epidemiological studies suggest a worldwide prevalence greater than 20%. Recently prostatitis has been classified into four categories based on the National Institutes of Health consensus classification: acute bacterial prostatitis, chronic bacterial prostatitis, chronic nonbacterial prostatitis/chronic pelvic pain syndrome (CP/CPPS), and asymptomatic prostatitis. CP/CPPS is subdivided into inflammatory and noninflammatory form. Prostatitis is a multifactorial disease with largely unknown aetiology. Although in most cases an infectious aetiology is accepted, there are major controversies about the diagnostic methods used and their interpretation. Yet, whether the inflammatory CP/CPPS is an infectious disease remains uncertain. The NIH Chronic Prostatitis Symptom Index represents the primary tool used to assess symptomatology. Diagnostic laboratory procedures include the four-glass test and the more practical two-glass test. According to the new NIH classification, pathogens can be cultured only in acute and chronic bacterial prostatitis. Diagnosis of acute and chronic bacterial prostatitis is primarily based on history, physical examination, urine culture, and urine specimen testing pre- and post-prostatic massage. Although there is a consensus on the diagnostic management of bacterial prostatitis (acute and chronic) in CP/CPPS the diagnostic approach remains unclear because inflammatory and non-inflammatory CP/CPPS might be one entity with varying findings over time and diagnosis is often based on exclusion of other urologic conditions. Thus, the bacterial infections are more readily recognized and treated, while patients with CP/CPPS are difficult to cure due to the unknown aetiology and complex clinical presentation of syndromes. Despite many advances in our understanding of the pathogenesis and treatment of prostatitis, current management strategies are unable to provide significant relief from the symptoms. Further studies on prostatitis syndromes pathogenesisΔελτίο Ελληνικής Μικροβιολογικής Εταιρίας. 09/2010; 55(5):375-384.