Article

[Relationship between liver fibrosis criteria and syndrome-type of TCM in patients with non-alcoholic fatty liver].

First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003.
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 09/2001; 21(9):652-3.
Source: PubMed

ABSTRACT To explore the relationship between the liver fibrosis criteria and TCM Syndrome, type in the patients suffering from non-alcoholic fatty liver.
Seventy-nine patients with non-alcoholic fatty liver diagnosed by B ultrasonography were classified by TCM Syndrome Differentiation and their liver fibrosis criteria was determined and compared with those of the health subjects as control.
Levels of procollagen III (PCIII), hyaluronic acid (HA), collagen IV (CIV) and laminin (LN) in the fatty liver group were significantly higher than those in the control group (P < 0.05, P < 0.01). In respect to the TCM Syndrome-types, PCIII, CIV and LN in patients of Phlegm-stasis combined type were significantly higher than those in patients of other two Syndrome-types (P < 0.05, P < 0.01), while HA was insignificantly different (P > 0.05).
There was trend of liver fibrosis in fatty liver patients. It was indicated that the Phlegm-stasis combined Syndrome-type possibly was the main TCM pathologic factor of the increasing of fibrosis criteria for non-alcoholic fatty liver.

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Keywords

B ultrasonography
 
CIV
 
collagen IV
 
control group
 
fatty liver group
 
fatty liver patients
 
fibrosis criteria
 
HA
 
health subjects
 
hyaluronic acid
 
liver fibrosis
 
liver fibrosis criteria
 
main TCM pathologic factor
 
non-alcoholic fatty liver
 
patients
 
Phlegm-stasis
 
procollagen III
 
TCM Syndrome
 
TCM Syndrome Differentiation
 
TCM Syndrome-types
 

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