Systemic 5-fluorouracil producing an inflammatory response in porokeratosis.

Boston University School of Medicine, Roger Williams Medical Center, Department of Dermatology and Skin Surgery, Providence, Rhode Island 02908, USA.
Journal of the European Academy of Dermatology and Venereology (Impact Factor: 2.69). 04/2003; 17(2):190-2. DOI: 10.1046/j.1468-3083.2003.00575.x
Source: PubMed

ABSTRACT Topical 5-fluorouracil has been used as an effective treatment for porokeratosis. Upon its treatment, an inflammatory effect occurs with the topical 5-fluorouracil. We report a case of a patient with disseminated superficial actinic porokeratosis displaying a comparable inflammatory process following therapy with systemic 5-fluorouracil used to manage a metastatic breast cancer.