Tetralogy of Fallot in a 2-year-old Holstein heifer.
ABSTRACT A 2-year-old, purebred Holstein heifer with exercise intolerance and cardiovascular compromise was diagnosed at postmortem with tetralogy of Fallot, which typically results in death within a few months of life. Survival past the age of 2 was unexpected. The concurrent endocarditis of the pulmonic valve is discussed.
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ABSTRACT: This study describes a case of tetralogy of Fallot in a lamb showing failure to thrive and signs of respiratory distress. Physical examination, electrocardiography, thoracic radiographies, echocardiography and cardiac troponin I evaluation were performed. The value of cardiac troponin I was compared with the values of 10 healthy lambs of the same age and breed, and the affected animal demonstrated an increase in cardiac troponin I. Due to the poor prognosis, euthanasia was indicated, and necropsy confirmed the diagnosis. This is the first report of an increase in cardiac troponin I in a lamb with tetralogy of Fallot.Journal of Veterinary Medical Science 05/2013; DOI:10.1292/jvms.13-0034 · 0.88 Impact Factor
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ABSTRACT: This report describes an unusual congenital anomaly found at postmortem in the pulmonary artery and vein of a 4-month-old female Holstein calf with clinical signs of congestive heart failure. Developmental abnormalities found included the pulmonary veins having two branches that opened into the right atrium instead of normal seven to eight, and the pulmonary artery had two branches in addition to the normal left and right branches that enter the lungs. This is the first confirmed case report of a congenital anomaly in the pulmonary artery and vein in the Holstein calf. KeywordsCongenital-Anomaly-Pulmonary-Vein-ArteryComparative Clinical Pathology 01/2010; 19(6):611-613. DOI:10.1007/s00580-009-0930-8
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ABSTRACT: Double outlet right ventricle is a conotruncal malformation where both great arteries (aorta and pulmonary trunk) arise from the right ventricle. A 2-month-old Holstein calf was slaughtered due to severe respiratory distress. At necropsy, the heart was enlarged, globose, and had ventricular and atrial septal defects. The only outlet for the left ventricle was a large ventricular septal defect located at 6cm distance from the heart apex and involved atrial septum too. The right ventricle was enlarged and markedly thickened with a left to right free wall ratio of 2.5:2 and prominent papillary muscles. The aorta arose from the right ventricular infundibulum adjacent to pulmonary trunk. Two valvular hematomas were observed on the edge of the right atrioventricular valve. The lungs were rubbery with ecchymotic and petechial hemorrhages and did not collapse after removing from thoracic cavity. Enhanced lobular pattern was evident on both the capsular and cut surfaces of the liver. Histopathological examination of the lungs revealed thickening of alveolar septa, hemorrhages, and infiltration of hemosiderophages within alveoli. Periportal hepatocellular fatty changes, substitution of centrilobular and midzonal hepatocytes by red blood cells, and dilation of midzonal and periportal sinusoids were seen in the liver. To our knowledge, this particular combination of cardiac defects has not been previously described in domestic animals and the pathological lesions observed in the calf may be resulted as a sequel to left–right blood shunting and heart failure.Comparative Clinical Pathology 01/2009; 18(2):187-189. DOI:10.1007/s00580-008-0771-x