Article

An eye on insulin.

Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania 17033, USA.
Journal of Clinical Investigation (Impact Factor: 13.77). 07/2003; 111(12):1817-9. DOI: 10.1172/JCI18927
Source: PubMed

ABSTRACT Diabetic retinopathy, the most frequent complication of diabetes and leading cause of vision loss, involves vascular and neural damage in the retina. Insulin and IGF-1 signaling are now shown to contribute to retinal neovascularization, in part, by modulating the expression of various vascular mediators.

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