Visualizing the Effect of Pentoxyphyllin Infusion Therapy on the Circulation of the Hand by Tc-99m DPTA Scintigraphy

Nuclear Medicine Department, University of Debrecen Medical and Health Center, Hungary.
Clinical Nuclear Medicine (Impact Factor: 3.93). 08/2003; 28(7):611-2. DOI: 10.1097/01.RLU.0000073608.95788.EF
Source: PubMed


Raynaud's phenomenon, manifested in episodic, vasospasm-originated, three-phase changes in the color of the fingers, is often a concomitant phenomenon of several autoimmune diseases, such as systemic sclerosis. In such patients, the circulation of the fingers can be affected in different degrees, including cases with serious disorders of the microcirculation, which lead to ulcers on the finger and possibly amputation. Pentoxifylline therapy, which improves circulation, may be effective in such cases. Tc-99m DPTA perfusion imaging of the hand can objectively visualize the circulation of the fingers and measure the effectiveness of therapy.

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