Article

Echocardiographic findings in subjects with psoriatic arthropathy.

Uludad University Medical Faculty, Department of Dermatology, Bursa, Turkey.
Journal of the European Academy of Dermatology and Venereology (impact factor: 2.98). 07/2003; 17(4):414-7. pp.414-7
Source: PubMed

ABSTRACT Psoriatic arthropathy (PA) is a seronegative arthropathy with a 5-20% prevalence among psoriatics. In recent years, cardiovascular abnormalities have been shown in patients with seronegative arthropathies.
Since echocardiography is a non-invasive method to evidence cardiac abnormalities, we planned a study to evaluate heart involvement in subjects with psoriatic athropathy using this method.
A total of 21 subjects (15 women, six men) aged from 34 to 71 years were involved in this study. After PA diagnosis was confirmed by skeletal scintigraphic survey, patients were evaluated by Doppler echocardiogram for cardiovascular disturbances and the results were compared with those for a sex- and age-matched control group.
The left ventricle end-diastolic and end-systolic diameters of the PA group were statistically different from those of the control group (P < 0.05), but no difference was observed in ejection fraction and the mitral E/A ratios. The presence of diastolic dysfunction was significantly related to the presence of arthropathy and the duration of psoriasis (P < 0.05).
We conclude that mild diastolic dysfunction may accompany PA but our data should be confirmed by further studies.

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Keywords

age-matched control group
 
Doppler echocardiogram
 
ejection fraction
 
end-systolic diameters
 
evidence cardiac abnormalities
 
heart involvement
 
left ventricle end-diastolic
 
men
 
mitral E/A ratios
 
non-invasive method
 
PA diagnosis
 
patients
 
psoriasis
 
Psoriatic arthropathy
 
psoriatic athropathy
 
psoriatics
 
recent years
 
seronegative arthropathies
 
seronegative arthropathy
 
skeletal scintigraphic survey