Bone involvement and abcess formation by neutrophil-rich CD30+anaplastic large-cell lymphoma mimicking skeletal infection in an AIDS patient

Hospital Universitario Virgen del Rocío, Hispalis, Andalusia, Spain
Journal of Infection (Impact Factor: 4.44). 08/2003; 47(1):73-6. DOI: 10.1016/S0163-4453(03)00005-7
Source: PubMed


Neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) is a rare pathological entity without distinct clinical behavior. Twelve cases of neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) have been reported, three of them were HIV-infected patients. All these reports stressed the presence of neutrophil infiltration as a new morphologic feature of CD30+ ALCL. Only one case of cutaneous involvement presented with microabscess formation. We describe a case of neutrophil-rich CD30+ ALCL in an AIDS patient with a clinical picture determined by the massive neutrophil infiltration of the tumor without necrosis nor local infection, but with the formation of abscesses.

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