Prevalence and Course of Schizophrenia in a Chinese Rural Area

Institute of Mental Health, West China Hospital, West China Medical School of Sichuan University, Chengdu.
Australian and New Zealand Journal of Psychiatry (Impact Factor: 3.41). 09/2003; 37(4):452-7. DOI: 10.1046/j.1440-1614.2003.01203.x
Source: PubMed


To assess the characteristics and factors affecting course of schizophrenia in a Chinese rural area.
An epidemiological investigation was conducted to identify all the patients with schizophrenia among 149 231 people in Xinjin County, Chengdu.
The total prevalence of schizophrenia was 4.13 per 1000 population. Males had an earlier mean age of onset (29.6 years) than females (32.3 years). Duration of illness before treatment and the total duration of illness were found to be significantly associated with level of remission. The status of treatment, family economy, housing, and families' care of patients had a significant effect on the clinical course of the illness.
Duration of illness before treatment may be an important predictor of course in schizophrenia. Early treatment for the patients may produce higher level of improvement in prognosis. Education intervention and community-based service are urgent priorities for these patients.

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Available from: Mao-Sheng Ran, Oct 04, 2015
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    • "In the People’s Republic of China, a recent large-scale study estimated the 1-month prevalence rate at 0.78%, with similar rates found in rural (0.80%) and urban (0.72%) areas.10 Other studies in the People’s Republic of China have reported prevalence estimates ranging approximately from 0.2% to 2.2%.9,11 The prevalence of schizophrenia in the People’s Republic of China appears to be similar to the global prevalence. "
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    ABSTRACT: This article describes the personal, societal, and economic burden attributable to schizophrenia in the People's Republic of China and highlights the potential for effective outpatient treatment to reduce this burden given recent changes in the Chinese health care system. The importance of effective antipsychotic therapy in reducing the burden of schizophrenia is also examined. Published research on the burden, disability, management, and economic costs of schizophrenia in the People's Republic of China was examined in the context of the larger body of global research. Research written in English or Chinese and published before June 2012 was identified using PubMed, CNKI, and Wanfang Med database searches. The contribution of effective antipsychotic therapy in reducing the risk for relapse and hospitalization and improving patients' functioning is described. Schizophrenia imposes a substantial burden on Chinese society, with indirect costs accounting for the majority of the total cost. Functional impairment is high, leading to lost wages and work impairment. In the People's Republic of China, schizophrenia is the most common diagnosis among hospitalized psychiatric patients. Ongoing changes in the Chinese health care system may reduce some barriers to effective relapse prevention in schizophrenia and potentially reduce hospitalizations. The use of antipsychotics for acute episodes and maintenance treatment has been shown to decrease symptom severity and reduce the risk for relapse and hospitalization. However, discontinuing antipsychotic medication appears common and is a strong predictor of relapse. Cost-effectiveness research in the People's Republic of China is needed to examine the potential gains from improved outpatient antipsychotic treatment. Schizophrenia is a very costly mental illness in terms of personal, economic, and societal burden, both in the People's Republic of China and globally. When treated effectively, patients tend to persist longer with antipsychotic treatment, have fewer costly relapses, and have improved functioning. Further research examining the long-term effects of reducing barriers to effective treatments on the societal burden of schizophrenia in the People's Republic of China is needed.
    ClinicoEconomics and Outcomes Research 08/2013; 5(1):407-18. DOI:10.2147/CEOR.S44325
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    • "The prevalence of schizophrenia in this study (0.49%) is lower than the findings of national (0.57% in 1982, Twelve-Region Psychiatric Epidemiological Study Work Group, 1986; 0.66% in 1993, Chen et al., 1998) and some regional psychiatric epidemiology studies in China (e.g. 0.65% in 1999 in Jiangxi province, Wan et al., 2002), but not all (0.30% in 1984 and 0.34% in 1994 in Shandong province, Weng et al., 1998; 0.41% in 1994 in Sichuan province, Ran et al., 2003). "
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    ABSTRACT: There has been no large-scale survey of schizophrenia in China involving both rural and urban areas using standardized assessment tools and diagnostic criteria. This study aimed to determine the lifetime prevalence of schizophrenia and its socio-demographic correlates in Beijing, China. A total of 5926 subjects were randomly selected in Beijing and interviewed using the Composite International Diagnostic Interview (CIDI 1.0). Basic socio-demographic and clinical data were collected during the interviews. The lifetime prevalence of schizophrenia was 0.49%, and 0.44% and 0.55% for men and women, respectively. Unmarried status, lower monthly income, urban abode and positive family history were associated with an increased risk of schizophrenia; 9.7% of the subjects with lifetime schizophrenia reported a history of suicide attempts. The percentage of subjects with schizophrenia who were receiving treatment and their preference to seek treatment from mental health professionals were 58% and 29%, respectively. National surveys are urgently needed to further explore the prevalence of schizophrenia in China. The low percentage of subjects treated for schizophrenia is a serious public health issue that should be addressed in the near future.
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