Article

Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine.

From Embrex Inc., 1040 Swabia Court, Research Triangle Park, NC 27709-3989, USA.
Journal of veterinary diagnostic investigation: official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (Impact Factor: 1.18). 08/2003; 15(4):361-4. DOI: 10.1177/104063870301500410
Source: PubMed

ABSTRACT A disease characterized by paresis and paralysis was seen in 7-9-day-old broiler chicks after vaccination in the neck area at day-of-age with a live virus vaccine containing viruses of Marek's disease, fowl pox, and infectious bursal disease. Affected birds presented with variable signs of ataxia, lateral recumbency, leg paralysis, and twisting or S-shaped flexure of the neck. Gross lesions noted at necropsy included swelling and edema of the subcutaneous tissues and muscles of the neck at the injection site area. A heavy mononuclear inflammatory cell infiltration was seen in the subcutaneous tissues, connective tissues, and muscles of the neck at the injection site. In some cases, the inflammatory process extended along fascial planes to involve the epidural spaces surrounding the spinal cord. Fatty changes with possible demyelination of nerve fibers were noted in some sections of the spinal cord adjacent to the inflammatory lesions. Clusters of poxviruses were found within some inflammatory lesions on transmission electron photomicrographs.

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    ABSTRACT: Ten-to-14-day-old replacement chickens were vaccinated subcutaneously in the neck with a Mycoplasma gallisepticum bacterin. A few days later, 40% of the flock developed cellulitis of the head. Birds were submitted for diagnostic investigation between 4 and 6 wk of age. Histology revealed lesions in the subcutis consistent with oil-emulsified vaccine/bacterin reaction. No significant bacteria were isolated from the lesions. Birds were treated with 1 mg of methyl prednisol acetate intramuscularly. Improvement was noted as early as 12 hr posttreatment. One week after treatment only 1%–2% of the flock still had facial cellulitis. Abbreviations: AI = avian influenza; IBD = infectious bursal disease; MG = Mycoplasma gallisepticum Reporte de Caso—Celulitis facial inducida en aves por la bacterina y el tratamiento contra Mycoplasma gallisepticum. Aves reproductoras de 10 a 14 días de edad fueron vacunadas por la vía subcutánea en la nuca con una bacterina contra Mycoplasma gallisepticum. Pocos días después, el 40% de la parvada desarrolló celulitis en la cabeza. Las aves fueron enviadas para la investigación diagnóstica entre las 4 y las 6 semanas de edad. La histología reveló lesiones subcutáneas asociadas con la reacción a la emulsión oleosa de las vacunas o bacterinas. No se aislaron bacterias importantes de las lesiones. Las aves fueron tratadas con un miligramo de prednisolona por la vía intramuscular. Se observó una mejoría a partir de las 12 horas después del tratamiento. Una semana después del tratamiento sólo el 1% al 2% del lote mostraba aún celulitis facial.
    Avian Diseases 01/2009; · 1.73 Impact Factor

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May 29, 2014