Only limited support for a role of psychosomatic factors in psoriasis - Results from a case-control study
To investigate the role of stressful events, social support, attachment security and alexithymia in triggering or exacerbating psoriasis.
Outpatients experiencing a recent onset or exacerbation of psoriasis (n=40) were compared with outpatients with skin conditions in which psychosomatic factors are regarded as negligible (n=116). Stressful events during the last year were assessed with Paykel's Interview for Recent Life Events. Attachment style, alexithymia and perceived social support were assessed with the ECR questionnaire, the TAS-20 and the MSPSS, respectively.
The mean number of recently experienced life events, or of undesirable, uncontrollable or major events was not different between psoriatic patients and controls. The only stress measure that showed a slight trend towards an association with psoriasis was having experienced four or more stressful events in the preceding year. There was a statistical trend towards an association between alexithymia and psoriasis, whereas there were no significant differences between patients with psoriasis and controls with respect to perceived social support and attachment security. Subgroup analysis suggested that the role of all psychosomatic factors studied might be more important in certain clinical types, such as guttate and diffuse plaque psoriasis.
Our findings provide only limited support for a role of psychosomatic factors in psoriasis. Future studies should investigate chronic and daily stressors in addition to major life events, include measures of stress appraisal and include specifically patients with a recent onset of disease.
Available from: Suleyman Akarsu
- "High sympathetic activity, high heart rate, high electrodermal activity, and low oxygen consumption were reported in alexithymic individuals (Guilbaud et al., 2003; Kauhanen et al., 1994). In a study by Picardi et al. (2003) in patients with alopecia areata, more alexithymic features, inadequate social support, and less close relationship have been reported. The majority of patients with alopecia areata who did not respond to treatment were shown to be alexithymic (Panconesi and Hautmann, 1996). "
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ABSTRACT: The aim of this study was to evaluate the primary focal hyperhidrosis patients in terms of alexithymia. Participants (n = 50) diagnosed with primary focal hyperhidrosis by a dermatologist were referred to a psychiatrist and evaluated via Structured Clinical Interview for DSM-IV Axis I Disorders and Toronto Alexithymia Scale-20. The rate of alexithymia was 45.6 percent and 18.2 percent, respectively, for primary focal hyperhidrosis and control participants (n = 44). Multivariate analysis of variance results showed that the primary focal hyperhidrosis group scored significantly higher than the control group in Difficulty Identifying Feelings and Difficulty Describing Feelings subscales, and total score. Psychotherapeutic interventions can increase the chances of dermatological treatment success and can have a positive impact on the quality of life in chronic cases.
Journal of Health Psychology 08/2012; 18(5). DOI:10.1177/1359105312454908 · 1.88 Impact Factor
Available from: PubMed Central
- "Among dermatologic diseases psoriasis is the most common disease that researchers were interested in exploring the relationship between alexithymia. The association of alexithymia and psoriasis was revealed in many studies4,22-24 whereas other studies failed to demonstrate a significant difference in alexithymic scores between patients with psoriasis and healthy controls.3,14,25 "
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ABSTRACT: To assess relationship between alexithymia and acne vulgaris in young people.
A hundred and eleven subjects between 15 and 25 years of age referred to out-patient clinic of dermatology with acne and 78 subjects applied to family physician for complaints other than acne were included in patient and control groups of the study, respectively. A questionnaire to determine demographic characteristics, an acne classification to determine severity of acne and Toronto Alexithymic Scale (TAS) to assess alexithymia were used.
The mean scores of TAS were 52.7±10.8 and 51.7±10.7 in patient and control groups, respectively. Alexitymia was determined in 23.4% of the subjects in acne group and in 24.4% of control group. No significant differences were found between groups in terms of alexithymia, intermediate alexitymia and three-factors of TAS.
Alexithymia does not appear to be related to acne vulgaris.
Psychiatry investigation 12/2011; 8(4):327-33. DOI:10.4306/pi.2011.8.4.327 · 1.28 Impact Factor
Available from: Mona Ståhle
- "The association between onset and exacerbation of psoriasis with stress is much debated and previous studies point in different directions. A recent study comprising 40 patients with mixed psoriasis phenotypes showed no evidence for an influence of stressful life events on psoriasis symptoms (Picardi et al, 2003), whereas other studies suggest a link between psycho-social stress and both onset and exacerbation of psoriasis (Naldi et al, 2001; Fortune et al, 2003). Obviously, more epidemiological and experimental research is needed to understand this potentially key issue in expression of psoriasis phenotype. "
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ABSTRACT: Psoriasis is clinically a heterogeneous disease. Detailed evaluation of phenotype at disease onset is lacking. This study is a baseline characterization of 400 adult individuals with first time incidence of psoriasis on non-hairy skin, describing clinical phenotypes and putative environmental triggers at disease onset. In total, 74 patients with guttate and 326 patients with non-guttate phenotype, the majority with plaque psoriasis, were included. Guttate phenotype was associated with younger age and recent infection in 84%, where acute streptococcal pharyngitis was verified in 63%. The predominating factor associated with onset of plaque psoriasis was a recent life crisis (46%). A positive family history for psoriasis was approximately the same in both groups. Psoriasis arthropathy was diagnosed in 5% of guttate and 15% of non-guttate patients, with enthesopathy being the dominant symptom among guttate patients. This study confirms the strong link between onset of guttate psoriasis phenotype and streptococcal throat infection, whereas onset of plaque psoriasis was highly associated with a preceding distinct stressful life event. Longitudinal follow-up of the patients will provide robust information about disease development and response to treatment.
Journal of Investigative Dermatology 04/2005; 124(3):499-504. DOI:10.1111/j.0022-202X.2004.23611.x · 7.22 Impact Factor
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