Article

Resuscitative challenges in nerve agent poisoning.

Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
European Journal of Emergency Medicine (impact factor: 0.9). 10/2003; 10(3):169-75. DOI:10.1097/01.mej.0000088428.19737.2e pp.169-75
Source: PubMed

ABSTRACT The threat of weapons of mass destruction such as nerve agents has become real since last year. The medical community has established protocols for the rapid evacuation and decontamination of affected civilians. However, protocols for resuscitative measures or acute perioperative care in cases of life-saving surgical interventions in toxic-traumatized casualties are still lacking. The database concerning the effects of nerve agent poisoning in humans is limited, and is largely based on reports of unintentional exposures to pesticide organophosphate poisoning and similar chemical substances. In this review, we summarize the knowledge on the possible pharmacological interactions between nerve agents and acute care.

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Keywords

acute perioperative care
 
decontamination
 
last year
 
life-saving surgical interventions
 
medical community
 
pesticide organophosphate poisoning
 
possible pharmacological interactions
 
protocols
 
rapid evacuation
 
resuscitative measures
 
similar chemical substances
 
toxic-traumatized casualties
 
unintentional exposures