Yuri F Babich

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• Question asked in Dermatopathology
  Open Electrodynamic Introscopy of living tissue: some illustrations and proposition
  In addition to my previous note, please, find some illustrations in our poster presented at the WC-2009 on medical physics and bioengineering,Munich (... [more]
  In addition to my previous note, please, find some illustrations in our poster presented at the WC-2009 on medical physics and bioengineering,Munich (attached). There is also a paper, but the poster has more illustrations. So, in short: we have an experimental setup of "Electrodynamic Introscope (EI)". As far as I know it is of a unique kind so far. With the aid of the EI we've detected some new phenomena of spatio-temporal features of living tissue, which might be used for various bio-medical purposes, e.g. oncology, gerontology. cosmetology, drug development, targeted/individualized therapy etc. Clear that these findings need to be verified with some conventional means, e.g. metabolic IR/PET mapping, electron microscopy for sub-cellular imaging etc. That's what I've been trying to organize here in Ukraine with tissue cultures. Unfortunately, due to the lack of relevant instrumentation (collapse of academic science), it looks to be hardly possibly in a human life span. Being verified, I believe, the EI approach might become of distinct commercial interest. So, as a minimal venture, we could propose (i) to bring the EI setup to a proper laboratory and carry out some preliminary trials - simultaneously and on the same tissues/subjects (or/and tissue cultures) that are under investigation, and (ii) to compare the results. As a matter of fact, we could do our scanning FIRST in order to reveal a general map of most suspicious micro-regions (metastasis, hypoxic/allergic/sensitive and any other functionally abnormal areas), which should be further investigated in detail with the aid of other imaging modalities.
  

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  By Yuri Babich ·
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• Question asked in Methods
  Open Novel phenomena of the Skin Electrophysiological Landscape (SEL) - where we might identify them? Yuri Babich
  With the aid of novel functional imaging modality - Electrodynamic Introscopy (EI) it turns out possible to reveal macroscopic manifestations of metab... [more]
  With the aid of novel functional imaging modality - Electrodynamic Introscopy (EI) it turns out possible to reveal macroscopic manifestations of metabolic and information processes happening at cellular and sub-cellular levels with a characteristic velocity of known calcium waves of inter-cellular communication, the abnormality of which are considered to be of sound oncodiagnostic value. As clearly visible lesions, we chose melanomas and nevi model objects and investigated the SEL dynamics of the tumor micro- and macro-environment both: initial and induced/contrasted by a number of test factors:weak MF, EMF, some drugs and, particularly, hypoxia. So it was possible to reveal a true tumor boundary, as some suspicious distant micro-regions of functionally weakened cell clusters. Our problem is that the EI is so far a unique technique and the discovered effects of living tissue functioning should be firstly confirmed with conventional laboratory means. We believe this EI technology might be of broad biomedical applications and would welcome any propositions for join-research investigations in this field. More detailed info can be provided to interested persons.
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• Answer added in Cancer Biology
  3 Novel phenomena of the Skin Electrophysiological Landscape (SEL) - where we might identify them?
  By Yuri Babich ·
  Yuri Babich ·

  Yes, we did some but not many and mainly short ones - partly because , here in Ukraine, we are very limited with modern laboratory means like e.g. P... [more]

  Yes, we did some but not many and mainly short ones - partly because , here in Ukraine, we are very limited with modern laboratory means like e.g. PET, light and IR and Raman microscopy. We had the 1st prise at WC1997 on medical physics and USA grant 2001-2004. The latest one was at WC2009 which you may find in Google "Visualization of the Skin Electrodynamic Landscape:Some Phenomenological Features in Norm and Oncopathology". (I failed to attach it here)
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• Question asked in Cancer Biology
  3 Novel phenomena of the Skin Electrophysiological Landscape (SEL) - where we might identify them?
  With the aid of novel functional imaging modality - Electrodynamic Introscopy (EI), it turns out possible to reveal macroscopic manifestations of meta... [more]
  With the aid of novel functional imaging modality - Electrodynamic Introscopy (EI), it turns out possible to reveal macroscopic manifestations of metabolic and information processes happening at cellular and sub-cellular levels with a characteristic velocity of known calcium waves of inter-cellular communication, the abnormality of which are considered to be of sound oncodiagnostic value. As clearly visible lesions, we chose melanomas and nevi model objects and investigated the SEL dynamics of the tumor micro- and macro-environment both: initial and induced/contrasted by a number of test factors: weak MF, EMF, some drugs and, particularly, hypoxia. So it was possible to reveal a true tumor boundary, as some suspicious distant micro-regions of functionally weakened cell clusters. Our problem is that the EI is so far a unique technique and the discovered effects of living tissue functioning should be firstly confirmed with conventional laboratory means. We believe this EI technology might be of broad biomedical applications and would welcome any propositions for joint-research investigations in this field. More detailed information can be provided to interested persons.
  By Yuri Babich ·
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