X. Long Zheng has
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Article: Structure-function and cofactor-dependent regulation of ADAMTS13 protease
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Article: Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII
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Article: Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: a report from the Southern Network on Adverse Reactions (SONAR).
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Department of Pathology and Laboratory Medicine
About
I am a clinical pathologist and physician scientist at the Children's Hospital of Philadelphia. I am also an associate professor in pathology and laboratory medicine, the University of Pennsylvania. My research focuses on pathogenesis of thrombotic thrombocytopenic purpura (TTP), inflammation, and atherosclerosis. Specifically, we are investigating the role of ADAMTS13 and ADAMTS7 metalloproteases in normal, thrombotic disorders, and cardiovascular diseases.