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I am a clinical pathologist and physician scientist at the Children's Hospital of Philadelphia. I am also an associate professor in pathology and laboratory medicine, the University of Pennsylvania. My research focuses on pathogenesis of thrombotic thrombocytopenic purpura (TTP), inflammation, and atherosclerosis. Specifically, we are investigating the role of ADAMTS13 and ADAMTS7 metalloproteases in normal, thrombotic disorders, and cardiovascular diseases.