Vipin Verma

Publications (2) View all

• Article: Immunostimulatory response induced by supplementation of Ficus benghalensis root powder, in the artificial feed the Indian freshwater murrel, Channa punctatus.

  Vipin Kumar Verma, Kumari Vandana Rani, Neeta Sehgal, Om Prakash
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  ABSTRACT: Methanol extract from the dried aerial root of Ficus benghalensis, was used to evaluate antibacterial activity on the bacterial strains of Aeromonas hydrophila and Escherichia coli, by disc diffusion method. In order to study, if there is any immunostimulatory response of F. benghalensis, immunized fish were fed with supplementary artificial feed containing 5% F. benghalensis dried root powder. There was no marked difference in the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in control and treated fish, suggesting that the supplementary feed had no adverse effect on liver or kidney. Serum lysozyme, tissue super oxide dismutase (SOD), percentage phagocytosis, phagocytotic index, nitric oxide (NO), total serum protein and immunoglobulin increased significantly in the treated fish compared to control fish. Serum immunoglobulin levels were estimated by development of a sandwich ELISA, and levels were found to increase with successive immunizations of BSA.
  Fish &amp Shellfish Immunology 07/2012; 33(3):590-6. · 3.32 Impact Factor
• Book: Hepatic Fibrosis: Attenuation by Picroliv and Andrographolide, Promotion towards herbal world

  Vipin Kumar Verma, Dr. Shashi Khandelwal
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  ABSTRACT: Hepatic damage is a major problem due to Viruses, Xenobiotics, toxic chemicals, environmental pollutants, contaminated water supplies and surface water can cause liver problems. Some harmful chemicals are also responsible for the hepatic fibrosis like CCl4, thioacetamide etc. The cure for this disease is not well established till now. Functionally liver is a detoxifying organ converts ammonia into urea through ornithine cycle because ammonia is highly toxic to the animal body. Present work gives information to promote the alternative herbal products rather than harmful chemo-therapeutics. Therapeutic role of two well known herbal components Picroliv from the roots of Picrorhiza kurroa and Andrographolide from the leaves of Andrographis Paiculata were used to cure the hepatic fibrosis in rats induced by administration of Thioacetamide which cause severe liver damage. Results represents the effective role of these plant components in curing Hepatic fibrosis without produce stress by itself.
  First 03/2012; LAP LAMBERT Academic Publishing, Germany., ISBN: 978-3848416653