Temidayo Soniran

Publications (5) View all

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  Available from: Temidayo Soniran

  Article: Evaluation of in vivo Antiplasmodial Activities of extracts of Morinda morindiodes (Bak.) in the treatment of malaria in Ogun State

  Soniran O Temidayo, Idowu Olufunmilayo, Idowu A Babatunde, Ajana Olusegun
  Malaria Journal 04/2012; 9:1-2. · 3.19 Impact Factor
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  Available from: Temidayo Soniran

  Article: Comparative Study on the Effects of Chloroquine and Artesunate on Histopathological Damages Caused by Plasmodium berghei in Four Vital Organs of Infected Albino Mice.

  O T Soniran, O A Idowu, O L Ajayi, I C Olubi
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  ABSTRACT: The aim of the present study was to investigate the positive influence of chloroquine and artesunate on the pathological damages caused by Plasmodium berghei on vital organs of mice in an established infection. Healthy adult albino mice with average weight of 25 g were used for the study. Treated group was administered orally with 100 mg/kg of chloroquine and artesunate, respectively. Control animals were given water for the same period. Histological examination of the liver, spleen, lungs, and kidney revealed absence of accumulation of iron (haemosiderosis) in the liver, thickened alveolar wall, and interstitial mononuclear cells infiltration in the lungs of the artesunate group, while absence of emphysema in the lungs and megakaryoblast hyperplasia in the spleen was observed in the chloroquine group. Lymphoid hypoplasia in the chloroquine group and megakayoblast hyperplasia in the artesunate group were observed but not in the control group. Thus, the use of these drugs especially under the practice of self-medication should be prohibited in lands where they are still in use as antimalaria medicine.
  Malaria research and treatment. 01/2012; 2012:960758.
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  Available from: Temidayo Soniran

  Article: DIABETES MELLITUS. A REVIEW.

  OZOUGWU J.C, SONIRAN O.T
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  ABSTRACT: Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action or both. In 2006, according to the World Health Organization, at least 171 million people world wide suffer from diabetes mellitus and is estimated that by the year 2030, this number will double. The major symptom of diabetes mellitus includes excessive thirst, frequent urination, increased appetite, weakness, fatigue and weight loss. Insulin is the principal hormone that regulates uptake of glucose into most cells from the blood and deficiency of insulin or insensitivity of its receptor cells plays a central role in all forms of diabetes mellitus. There are two major types of diabetes mellitus namely type 1 diabetes and type 2 diabetes. The complication of diabetes mellitus includes long-term damage, dysfunction and failure of various organs of the body. Some risk factors of diabetes mellitus include genetic predispositions, obesity and age. The primary goal in the management of diabetes is to control blood sugar levels. In the type 1 Diabetics, this requires regular insulin injections whereas in type 2 diabetes dietary modification is required. Breastfeeding has been documented to decrease the risk of type 1 diabetes while type 2 diabetes risks can be reduced by making changes in diet and increasing physical activity. To stem the economic, social and health implications of diabetes mellitus, the government of member nations of the United Nations should encourage more research on diabetes mellitus especially researches exploiting different treatment options like herbal medicine. It is also necessary to subsidies the cost of oral hypoglycaemic drugs and insulin injections used by diabetics especially in developing countries so that diabetics can easily afford them.
  Pharmacologyonline 11/2011; 2:531-543.
• Article: Evaluation of in vivo Antiplasmodial Activities of extracts of Morinda morindiodes (Bak.) in the treatment of malaria in Ogun State

  Soniran Temidayo, Idowu Olufunmilayo, Idowu Babatunde, Ajana Olusegun
  Malaria Journal. 01/2010;
• Article: Parasitic infections in finger-sucking school age children.

  Olufunmilayo Ajoke Idowu, Omolayo Babatunde, Temidayo Soniran, Adekunle Adediran
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  ABSTRACT: Prevalence of parasites, acquired by the fecal-oral route, was recorded in 80% of primary school children with a finger-sucking habit, which was higher than that in nonfinger-sucking children. About 85% of the children did not wash their hands after defecation. The toilet facility available to the children also affected the infection pattern in finger-sucking children who used pit latrines recording higher prevalence of parasites.
  The Pediatric Infectious Disease Journal 05/2011; 30(9):791-2. · 3.58 Impact Factor