Research: Apollo HospitalsApollo HospitalsIndia · Chennai
J&KMS (Surgery )India · Jammu
Awards & achievements
Question asked in OncologyOpen Therapeutic targeting of Apoptitic cell death in GI CancerWould like to discuss about the imaging and therapeutic targeting of apoptotic cell death in GI Cancers, especially colonic cancers viz.viz reversing ... [more]Would like to discuss about the imaging and therapeutic targeting of apoptotic cell death in GI Cancers, especially colonic cancers viz.viz reversing p53 resistance .By Sunil Kaul · Inderprastha Apollo Hospitals, New-DelhiFollowing
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ABSTRACT: Primary hyperhidrosis is a disorder that is characterized by excessive sweating in disproportion to that required for thermoregulation. In most cases, this is aggravated by emotional factors and by heat. Hyperhidrosis can be seen in the palms of the hands, armpits, soles of the feet and face. The principal characteristic of this disease is the intense discomfort of patients, which affects their social and professional life. Treatment modalities include topical application of aluminum chloride, iontophoresis, anticholinergics, botulinum toxin injection, liposuction, excision of sweat glands, and thoracic sympathectomy. Between January 1998 and August 2007, a prospective study of endoscopic thoracic sympathectomies for palmar hyperhidrosis was undertaken based on case histories and a prospective pre- and postoperative questionnaire survey. The sample comprised of 322 patients with a mean age of 24 years. At Apollo Hospital, New Delhi, India, bilateral video-assisted thoracoscopic T3 level sympathectomies were performed in all cases. All patients had immediate cessation of palmar hyperhidrosis. The mean postoperative stay was 1.1 days. A questionnaire was completed based on their response to a telephone conversation or e-mail. A paired t test and Wilcoxon test was performed on these data and it showed significant improvement in quality of life. Compensatory sweating was found to be the most troublesome side effect for all patients. It was seen in 63% of the patients. This is similar to other reports of compensatory sweating; however, the figure decreases to 29% if we disregard the percentage of patients who reported only mild compensatory sweating. In view of the low morbidity and zero mortality rate of this surgical technique, we recommend it as a method of treatment for palmar hyperhidrosis. Thoracic sympathectomy eliminates palmar hyperhidrosis with minimal recurrence (1% in our series) and produces a high rate of patient satisfaction.Surgical Endoscopy 08/2010; 24(8):1952-7. · 4.01 Impact Factor
Article: Thoracoscopic splanchnicectomy as a palliative procedure for pain relief in carcinoma pancreas.[show abstract] [hide abstract]
ABSTRACT: Thoracoscopic splanchnicectomy has been used for the management of upper abdominal pain syndromes as an alternative to celiac plexus block for conditions such as chronic pancreatitis or supramesocolic malignant neoplasms, including unresectable pancreatic cancer. This procedure is similar to the percutaneous block with a higher degree of precision and avoids the side effects associated with the local diffusion of neurolytic solutions. Thoracoscopic splanchnicectomy appears to be a better treatment in such cases as the procedure is done under direct vision and less dependent on anatomical variations.Journal of Minimal Access Surgery 05/2009; 5(2):37-9.