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  • Article: Health-related quality of life of patients with epilepsy in Turkey.
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    ABSTRACT: The aim of this study was to measure the health related quality of life (HRQOL) of epilepsy patients and to compare it with that of a healthy control group. The evaluation included the effects of the type of seizure, duration of seizure and medical treatment on the quality of life of the patients. The group studied consisted of 221 participants (121 epilepsy patients and 100 healthy control individuals) who completed a sociodemographic data form and who were administered the World Health Organization Quality of Life (WHOQOL-100) scale. The epilepsy patients had statistically lower physical health, psychological well-being, level of independence and global HRQOL than participants in the control group (p<0.05). The analysis of variance showed that the partial epilepsy subgroup had significantly lower averages for all the quality-of-life subfields except for the social relationship dimension. On regression analysis, being married, having a generalized type of seizure and being treated with fewer medications were all related to higher scores on the HRQOL. Epilepsy is a disease that has neurological, psychiatric and psychosocial dimensions that should be evaluated using a multidisciplinary approach.
    Journal of Clinical Neuroscience 10/2009; 16(12):1582-7. · 1.25 Impact Factor
  • Article: Spontaneous primary intraventricular hemorrhage in adults: clinical data, etiology and outcome.
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    ABSTRACT: Primary intraventricular hemorrhage (PIVH), bleeding in the ventricular system without a recognizable parenchymal component, is a rare neurological disorder. The purpose of this study was to identify clinical features, risk factors, etiology and outcome of patients with PIVH. We retrospectively reviewed the clinical data, complementary examinations, outcome and computed tomography (CT) IVH score of 24 patients in our hospital from 2004 to 2008. We identified 24 patients with the inclusion criteria of non-traumatic PIVH. Their mean age was 60.6+/-17.4 years (range 38-79). Fourteen patients were male and 10 were female. The major symptoms included headache (n=24), loss of consciousness (n=6), confusion and disorientation (n=14), nausea/vomiting (n=10). Angiography revealed vascular malformations in five patients (21%). Other possible causative factors were hypertension in 12 patients (50%) and clotting disorder in one. The aetiology remained unknown in six patients. Most PIVH patients had associated hydrocephalus (58%) and 37% of the patients required ventricular drainage. In-hospital mortality was high (41%) and a FOUR score <or=10, GCS <or=8 and early hydrocephalus were independent predictors of mortality. Hypertension is the most common associated risk factor for PIVH followed by vascular malformation. Spontaneous resorption and rebleeding may be seen. The neurological status of the patients and an early developing hydrocephalus are the most important risk factors.
    Turkish neurosurgery 10/2009; 19(4):338-44. · 0.62 Impact Factor
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    Article: Hypertensive encephalopathy with atypical MRI leukoencephalopathy affecting brain stem and cerebellum.
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    ABSTRACT: Reversible posterior leukoencephalopathy syndrome associated with hypertension rarely presents with predominant involvement of the brainstem and sparing of the supratentorial regions. In this study, the clinical and neuroimaging features of a 39-year-old woman with hypertensive encephalopathy and magnetic resonance imaging (MRI) findings localized to pons and bilateral middle cerebellar peduncles were described. Reversible posterior leukoencephalopathy syndrome associated with hypertension rarely shows isolated brainstem and cerebellum involvement, and it is important to be familiar with the lack of correlation between the severity of the radiological abnormality and the clinical status.
    Acta neurologica Belgica 07/2009; 109(2):142-5. · 0.54 Impact Factor
  • Article: Endovascular Treatment of Extracranial Internal Carotid Artery Stenosis
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    ABSTRACT: --------------------------------------------------------------------------------Purpose The purpose of this study is to present first year experience of a center on carotid artery stenting under filter-type protection devices, on 29 patients. Material-Methods We have performed 30 carotid stenting under filter-type distal protection systems, in 29 cases. The age range was 51-76 (mean age 65.66±6.28), 5 of the cases were female and 24 were male. Results The stenting procedure was technically successful in all of the cases. In one of the case use of second stent was necessary due to stent migration. There were no transient or permanent neurologic signs observed. Conclusion Stroke is the third most common cause of all deaths and internal carotid artery bulb stenosis is an important source of stroke. Carotid artery stenting has become a standard treatment of atherosclerotic carotid artery disease, but procedure related intracranial embolization remains a limitation of technique. In the presented study, we have used nonocclusive-filter type distal protection devices. Experience of operator and center is closely related success rate. In this study, we are presenting the first year experience of a new interventional neuroradiology center, documenting the cases, sharing the difficulties and discussing about the results and follow-up.
    Journal of Neurological Sciences. 01/2005;
  • Article: Ischemic stroke and subarachnoid hemorrhage due to spontaneous vertebral artery dissection: Three cases
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    ABSTRACT: Dissection of vertebral arteries is increasingly being recognized as a cause of ischemic stroke and /or subarachnoid hemorrhage. Although head and neck trauma and primary diseases of arterial wall are predisposing factors, it can occur spontaneously. Headache and/ or neck pain with vertigo is important warning sign that may precede onset of stroke by several days. We described three patients with spontaneous vertebral artery dissection who had neck pain as presenting symptom. All patients had hypertension. Two of them (44 year-old male and 40 year- old female) had transient ischemic attack followed by stroke. 66-year old male patient had subarachnoid hemorrhage due to intracranial dissection of vertebral artery. We conclude that spontaneous vertebral artery dissection should be suspected in all patients presenting neck pain with posterior circulation ischemic stroke or SAH but without trauma history.
    Journal of Neurological Sciences. 01/2004;

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