Salih Ozgocmen

Publications (91) View all

• Source

  Available from: Ewa Stanislawska-Biernat

  Article: 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis.

  J Braun, R van den Berg, X Baraliakos, H Boehm, R Burgos-Vargas, E Collantes-Estevez, H Dagfinrud, B Dijkmans, M Dougados, P Emery, [......], W P Maksymowych, I Olivieri, K Pavelka, J Sieper, E Stanislawska-Biernat, D Wendling, S Ozgocmen, C van Drogen, Bj van Royen, D van der Heijde
  [show abstract] [hide abstract]
  ABSTRACT: This first update of the ASAS/EULAR recommendations on the management of ankylosing spondylitis (AS) is based on the original paper, a systematic review of existing recommendations and the literature since 2005 and the discussion and agreement among 21 international experts, 2 patients and 2 physiotherapists in a meeting in February 2010. Each original bullet point was discussed in detail and reworded if necessary. Decisions on new recommendations were made - if necessary after voting. The strength of the recommendations (SOR) was scored on an 11-point numerical rating scale after the meeting by email. These recommendations apply to patients of all ages that fulfill the modified NY criteria for AS, independent of extra-articular manifestations, and they take into account all drug and non-drug interventions related to AS. Four overarching principles were introduced, implying that one bullet has been moved to this section. There are now 11 bullet points including 2 new ones, one related to extra-articular manifestations and one to changes in the disease course. With a mean score of 9.1 (range 8-10) the SOR was generally very good.
  Annals of the rheumatic diseases 06/2011; 70(6):896-904. · 8.11 Impact Factor
• Article: Can the patient-reported outcome instruments determine disease activity in rheumatoid arthritis?

  B Durmus, Z Altay, O Baysal, Y Ersoy, A Erdal, R Cevik, O Ardicoglu, I Tekeoglu, K Yildirim, A J Sarac, A Kamanli, S Karatay, K Nas, A Kaya, K Senel, A Gur, M Ugur, S Ozgocmen
  [show abstract] [hide abstract]
  ABSTRACT: The aim of this study was to investigate the indicative value of the patient-reported outcome instruments (PROs) on disease activity in rheumatoid arthritis (RA). Three hundred sixty eight patients with RA were included in this cross-sectional study. Disease activity was evaluated using both the Disease Activity Score 28 (DAS 28) and the Clinical Disease Activity Index (CDAI). Patients who had DAS 28 score < 3.60 points and CDAI score <10.00 points were allocated into the "low disease activity" group and those who had DAS 28 score > or = 3.60 points and CDAI score > or = 10.00 points into the "moderate or high disease activity" group. The Health Assessment Questionnaire (HAQ), Nottingham Health Profile (NHP), Rheumatoid Arthritis Quality of Life (RAQoL), and Short Form 36 (SF 36) were used as PROs. Logistic regression analysis was used to find variables, which had an indicative value for disease activity. HAQ, pain and emotional reaction subscales of NHP, and bodily pain, general health and social functioning subscales of SF 36 had independent indicative values, when DAS 28 was used as dependent variable. On the other hand, HAQ, pain and emotional reaction subscales of NHP, and general health and emotional role limitation subscales of SF 36 had indicative values when CDAI was used as dependent variable. DAS 28 and CDAI both showed HAQ as the parameter with the highest odds ratio (OR). But RAQoL had shown no independent indicative value for projecting disease activity. It was concluded that HAQ could determine disease activity in RA better than other PROs included in this study (Tab. 4, Ref. 36).
  Bratislavske lekarske listy 01/2011; 112(10):555-61. · 0.40 Impact Factor
• Article: MR-defined fat infiltration of the lumbar paravertebral muscles differs between non-radiographic axial spondyloarthritis and established ankylosing spondylitis.

  Ozgur Akgul, Arif Gulkesen, Gurkan Akgol, Salih Ozgocmen
  [show abstract] [hide abstract]
  ABSTRACT: OBJECTIVE: The aim of our study was to compare the magnetic resonance imaging (MRI)-defined cross-sectional area and semi-quantitative grading of fatty degeneration of lumbar paravertebral muscles in patients with non-radiographic axial spondyloarthritis (nr-axSpA) and established ankylosing spondylitis (AS). METHODS: Cross-sectional area (CSA) of lumbar paravertebral muscles, including the right and left multifidus (MF), erector spina (ES), psoas (PS), vertebral body and muscle:vertebra ratio (MVr), was measured. Fat infiltration of the paravertebral muscles was graded semi-quantitatively. RESULTS: The CSA of the MF, ES and PS muscles and the MVr (at the L2, L3, L4 and L5 levels) were quite similar between patients with nr-axSpA (n = 14) and AS (n = 22). However, patients with AS had higher grades of fat infiltration than those with nr-axSpA (Right L4 grading of MF + ES muscles: 1.4 ± 0.73 vs. 0.51 ± 0.52, respectively, p = 0.001; left L4 grading: 1.36 ± 0.65 vs. 0.38 ± 0.50, respectively, p < 0.0001). This difference remained significant after adjusting for age and symptom duration. The inter-rater reliability was good (intraclass correlation coefficient 0.75 and 0.85). CONCLUSIONS: This is first study demonstrating that MRI-defined fatty degeneration differs between patients with nr-axSpA and established AS. Semi-quantitative grading is reliable, and fatty degeneration of paravertebral muscles seems to be related to chronicity and spinal functions in patients with nr-axSpA and AS.
  Modern Rheumatology 09/2012; · 1.58 Impact Factor
• Article: Prevalence of atopic disorders in rheumatic diseases.

  Saliha Karatay, Kadir Yildirim, Mahir Ugur, Kazim Senel, Akin Erdal, Bekir Durmus, Ozlem Baysal, Zuhal Altay, Aysegul Jale Sarac, Ali Gur, Ozge Ardicoglu, Ayhan Kamanli, Remzi Cevik, Arzu Kaya, Yuksel Ersoy, Kemal Nas, Salih Ozgocmen
  [show abstract] [hide abstract]
  ABSTRACT: OBJECTIVES: The aim of this study was to assess the point prevalences of hay fever, asthma, and atopic dermatitis in OA, RA, and AS, and to compare with healthy controls. METHODS: A total of 935 patients and healthy controls were included. Demographic and clinical features were recorded, and a questionnaire assessing the existence of atopic disorders like asthma, hay fever, and atopic dermatitis in all groups was applied. "Either atopy" implied that an individual was either diagnosed with or had symptoms of one or more of these disorders, such as asthma, hay fever, or atopic dermatitis. RESULTS: When compared to the controls, only patients with AS had an increased risk for hay fever (OR 1.52, 95 % CI 1.00-2.41). Patients with RA had increased risks for hay fever, atopic dermatitis, and either atopy compared to the patients with OA (2.14, 95 % CI 1.18-3.89; 1.77, 95 % CI 1.00-3.18; and 3.45, 95 % CI 1.10-10.87, respectively). Steroid use had no effect on the prevalence of atopic disorders in patients with RA. CONCLUSIONS: Patients with OA, RA, and AS seem to have similar risks for asthma, atopic dermatitis, and either atopy to healthy controls. However, the prevalence of hay fever may increase in AS. Patients with RA have a higher risk of atopy than patients with OA.
  Modern Rheumatology 05/2012; · 1.58 Impact Factor
• Source

  Available from: Faruk Sendur

  Article: Agreement of Turkish physiatrists with the assessment in spondyloarthritis international society and the European league against rheumatism recommendations for the management of ankylosing spondylitis and rheumatoid arthritis.

  Salih Ozgocmen, Ozgur Akgul, Aysen Akıncı, Sebnem Ataman, Murat Birtane, Hatice Bodur, Rezan Günaydın, Omer Kuru, Aylin Rezvani, Omer Faruk Sendur, Kazım Senel, Tiraje Tuncer
  [show abstract] [hide abstract]
  ABSTRACT: New developments in the field of targeted therapies or biologic agents led more effective management of ankylosing spondylitis (AS) and rheumatoid arthritis (RA). Recommendations for the management of rheumatic diseases propose to reduce inappropriate use of medications, minimize variations among countries, and enable cost-effective use of health care resources. The aim this study was to evaluate conceptual agreement of ASsessment in SpondyloArthritis International Society (ASAS) and the EUropean League Against Rheumatism (EULAR) recommendations for the management of AS and EULAR recommendations for RA and to assess the rate of application among Turkish physiatrists in daily clinical practice. An online survey link has been sent to 1756 Turkish physiatrists with e-mails asking to rate agreement on 11-item ASAS/EULAR AS recommendations and 15-item EULAR RA recommendations with synthetic and biological disease-modifying anti-rheumatic drugs. Also barriers and difficulties for using biologic agents were assessed. Three hundred nine physiatrists (17.5%) completed the survey. The conceptual agreement with both recommendations was very high (Level of agreement; mean 8.35±0.82 and 8.90± 0.67 for RA and AS recommendations, respectively), and the self-declared application of overall recommendations in the clinical practice was also high for both RA and AS (72.42% and 75.71%, respectively). Turkish physiatrists are in good conceptual agreement with the evidence-based recommendations for the management of AS and RA. These efforts may serve to disseminate the knowledge and increase the current awareness among physicians who serve to these patients and also implementation of these recommendations is expected to increase as well.
  The Open Rheumatology Journal 01/2012; 6:1-5.