[show abstract][hide abstract] ABSTRACT: A new asymmetric heptaaza Schiff base macrocyclic bis(pendant donor) manganese(II) complex, [MnL(1)](ClO(4))(2).CH(3)CN (1), has been prepared and characterized by X-ray diffraction and spectroscopic methods. The antimicrobial activity of 1 and a series of its familiar symmetric heptaaza pydieneN(5), pydieneN(5), and pydieneN(5)-based bis-(2-aminoethyl) pendant armed Schiff base macrocyclic complexes of Mn(II) were tested against Escherichia coli, Staphylococcus aureus and Candida albicans. The results showed that the symmetric heptaaza pydieneN(5), and pydieneN(5)-based Schiff base macrocyclic complexes of Mn(II) had remarkable inhibition zone on the culture of S. aureus and E. coli as compared with standard drugs. The optimized geometry of the prepared complex has been obtained from density functional method, DFT, using B3LYP/6-31G* basis set.
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 10/2010; 77(2):342-7. · 2.10 Impact Factor