Skills (28)
Research experience
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Aug 2010–
presentResearch: University of Florida
University of Florida · Biomedical & Health Information ServicesUSA · Gainesville
Education
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Sep 2008–
May 2011Southern Connecticut State Universirty
Academic libraries · MLISUnited States of America (USA) · New Haven -
Sep 1987–
Jun 1992University of Havana
Biology · BS BiologyCuba · Havana
Other
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LanguagesSpanish, Portuguese, French
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Scientific MembershipsMedical Library Association
Special Libaries Association
American Library Association -
Journal RefereesJournal of e-Science Librarianship
Questions and Answers (236) View all
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Answer added in Cancer Cell Line15 Why are my RAW 264.7 cells floating?I agree with Gary Gilmore. Here is the recommended culture method by ATCC for this cell line: "Complete Growth Medium The base medium for this cell l... [more]
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Answer added in Cancer Cell Line1 Do adherent KU812F basophilic cells exist?Hi Shanna, According to the author that isolated these cells: "Growth of the liquid cultured cells was initiated within a week and their doubling time... [more]
Publications (9) View all
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Article: Detection and typing of human papillomavirus DNA in benign and malignant tumours of laryngeal epithelium.
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ABSTRACT: The role of human papillomaviruses (HPV) in laryngeal squamous cell carcinoma has not yet been established. Thirty-three cases of laryngeal squamous cell carcinoma were analysed for the presence of HPV DNA and compared with 25 cases of normal larynx and 29 cases of laryngeal squamous papilloma in their positivity index. The presence of HPV DNA was analysed by using L1 consensus primers and also by primers specific for the E7 gene of HPV types 16 and 18. Four normal laryngeal samples (16%) were positive for HPV DNA against the 24 samples (82%) (p < 0.001) found for laryngeal papilloma and 16 (48.5%) (p < 0.05) found for laryngeal squamous cell carcinoma. HPV 16 was the type most frequently found in laryngeal carcinoma samples. Our results support an etiologic role for this type of HPV in the pathogenesis of laryngeal carcinoma.Acta Oto-Laryngologica 10/1998; 118(5):754-8. · 1.08 Impact Factor -
Article: [Genetic expression of nerve growth factor in the central nervous system. Evaluation of an experimental model for Alzheimer's dementia].
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ABSTRACT: Several authors have suggested that loss of neuronal trophic support may be an important element in the physiopathology of degenerative conditions of the central nervous system such as Alzheimer's dementia, Parkinson's disease or amyotrophic lateral sclerosis amongst others. In the light of present knowledge, the survival of cholinergic populations of the anterior basal cerebrum, closely involved with cognitive processes of memory and learning, is associated with adequate function of the neural growth factor (NGF). These populations are markedly damaged in Alzheimer's disease, and this has been correlated with the progressive loss of memory and intellectual involvement seen in this disorder. The model used in this study was based on section of the septohippocampal connecting pathways, so that transport of regulatory impulses from the hippocampus to the medial septum was interrupted. This has lethal results for the cholinergic neurons of the latter. We have developed a study designed to characterize the expression of the gene of NGF in different regions of the brain, involved in cholinergic neurotransmission in healthy and in damaged tissue. We used a molecular hybridization technique with a cDNA catheter complementary to the radio-isotope marked NGF human gene. The highest levels of expression were found in the healthy cortex and hippocampus. The reduction in the levels of mRNA of NGF in the damaged hippocampus supports the current thesis which considers synaptic activity to be a major regulator of the synthesis of this molecule in the brain.Revista de neurologia 03/1998; 26(150):204-7. · 0.65 Impact Factor -
Article: Molecular analysis of resistance to interferon in patients with laryngeal papillomatosis.
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ABSTRACT: Although interferon (IFN)-alpha has been used successfully as an adjuvant therapy in laryngeal papillomatosis, some patients are resistant to this treatment. In order to know which patients will benefit from the therapy, we have tried to find a relationship between the IFN response and the viral and host parameters in the lesion. Detection of viral type and copy numbers by polymerase chain reaction (PCR) showed that all patients infected with human papillomavirus (HPV)-11 were sensitive to the treatment, in contrast to those infected with HPV-6. These differences could be explained in part by the inability of HPV-11 E7 to inhibit the induction of an IFN-responsive element, whereas HPV-6 E7 almost completely inhibited the activity of this promoter in transient transfection experiments. Local immune status in the lesion showed that all HPV-11-infected patients had detectable levels of interleukin (IL)-15 and IFN-gamma mRNA, in contrast to HPV-6-infected patients, in whom mRNA for these cytokines was almost absent. Viral copy numbers and levels of IL-4 mRNA could not be correlated with IFN response. Only one patient resistant to recombinant IFN-alpha2b and negative for HPV DNA presented high titers of neutralizing anti-IFN-alpha2b antibodies. This patient became sensitive when natural IFN-alpha was administered. These results suggest that response to IFN may be a complex phenomenon resulting from the interaction between viral and host elements.Cytokines Cellular & Molecular Therapy 07/1999; 5(2):79-85. -
Article: The presence of academic health sciences libraries on Facebook: the relationship between content and library popularity.
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ABSTRACT: Social networks such as Facebook allow libraries to be proactive in reaching their users. While some libraries have popular Facebook pages, it remains unclear what attracts users to these pages. This study evaluates relationships between libraries' Facebook page content and popularity. An analysis of 72 academic health sciences libraries' Facebook pages showed positive correlations between number of library fans and number of tabs, photos, events, and wall posts on Facebook. Libraries posting videos had significantly more fans than libraries without them. This study contributes to an understanding of correlations between content and popularity on Facebook, with implications for library outreach.Medical Reference Services Quarterly 04/2012; 31(2):171-87. -
Patent: METHOD FOR OBTAINING MICROORGANISMS CAPABLE OF PRODUCING ANTITUMOR MOLECULES
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ABSTRACT: Obtaining of producer microorganisms of antitumor molecules. This invention is related with the field of Biotechnology and particularly with a procedure for obtaining producer microorganisms of antitumor molecules. The objective of the present invention is to achieve a method for obtaining producer microorganisms of antineoplastic molecules that could be useful for the treatment of tumor disorders and it consists in the confrontation of microbial strains with tumor cells in proper hosts. This invention could be used for obtaining antitumor molecules.Ref. No: WO/1998/014566, Year: 01/1998
