Research: Immunotherapy for head and neck cancerEarle A Chiles Research Institute at Providence Cancer Center · Providence Oral Head and Neck Cancer Program · Robert W. Franz Cancer Research CenterUSA · Portland, Oregon
Research: Oregon Health and Science UniversityOregon Health and Science University · Department of Oral and Maxillofacial SurgeryUSA · Portland
Research: University of North Carolina at Chapel HillUniversity of North Carolina at Chapel Hill · School of DentistryUSA · Chapel Hill
Research: University of Nebraska at OmahaUniversity of Nebraska at OmahaUSA · Omaha
Article: Zygoma reconstruction.[show abstract] [hide abstract]
ABSTRACT: Ideal reconstruction of the zygoma position is essential in restoring facial width, projection, and symmetry. Reconstruction should be focused on the zygoma's 4 articulations and restoring the vertical and horizontal pillars of the facial skeleton. This article describes the applied surgical anatomy as it relates to zygomatic deformities, surgical approaches, and reconstruction. The basis for diagnosing and classifying zygoma deformities as they relate to severity of injury and associated displacement, comminution, and comorbidities is also discussed. Traditional and contemporary concepts in posttraumatic, postablative, and esthetic reconstruction are also described.Oral and maxillofacial surgery clinics of North America 05/2013; 25(2):167-201.
Article: Thin Serial Step Sectioning of Sentinel Lymph Node Biopsy Specimen May Not Be Necessary to Accurately Stage the Neck in Oral Squamous Cell Carcinoma.[show abstract] [hide abstract]
ABSTRACT: PURPOSE: The purpose of this study was to assess the predictability of sentinel lymph node biopsy (SNB) for oral squamous cell carcinoma (OSCC) when pathologic processing is performed without serial step sectioning. MATERIALS AND METHODS: We prospectively enrolled 36 patients with T1 or T2 cN0 OSCC into this institutional review board-approved prospective cohort study, and they underwent gamma probe-guided SNB in addition to selective neck dissection. The rate of patients with negative SNB results whose neck dissection was also negative for metastasis (negative predictive value) was the primary endpoint. RESULTS: Of the 28 patients whose sentinel lymph nodes were found to be pathologically and clinically node negative by routine hematoxylin-eosin stain and immunohistochemistry, 27 were found to have no other pathologically positive nodes, corresponding to a negative predictive value of 96%. CONCLUSION: The results of this study suggest that SNB performed without the use of thin serial step sectioning may accurately predict neck stage in OSCC.Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 02/2013; · 1.58 Impact Factor
Nicholas G Conger, Marcus H Colyer, Jon C Clasper, Kent E Kester, Gregory J Martin, Laurie C D'Avignon, Leon E Moores, William T Obremskey, Warren C Dorlac, Clinton K Murray, [......], Helen K Crouch, John M Cho, Timothy J Whitman, Andrew R Wiesen, David K Hayes, Thomas K Curry, Joseph R Hsu, Glenn W Wortmann, Kevin K Chung, John B Holcomb
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ABSTRACT: Oropharyngeal cancer was traditionally treated with en bloc resection of the tumor via lip-split mandibulotomy approach, often with adjuvant radiation and chemotherapy. In the 1990s, organ-sparing definitive chemoradiation therapy without surgery became the standard of care for oropharyngeal squamous cell carcinoma. Although organ-sparing treatment provided acceptable locoregional disease control with preservation of anatomic organs adjacent to the tumors and less disfiguration from lack of surgical incisions, it often resulted in significant deficits in speech and swallowing. This article reviews a current organ-and-function preserving approach to oropharyngeal carcinoma using the surgical robot.Oral and maxillofacial surgery clinics of North America 12/2012;
Michael R Markiewicz, R Bryan Bell[show abstract] [hide abstract]
ABSTRACT: Traditional orbital approaches are nearly a century old and still comprise the foundation of techniques used today. Computer-assisted planning and intraoperative navigation have recently been reported with more prevalence in the literature. The purpose of this article was to review commonly used approaches to the orbit: old and new.Oral and maxillofacial surgery clinics of North America 11/2012; 24(4):573-607.